ACY3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ACY3 at tissue level.

III. Associated gene sets

GO_0008150Biological processbiological_process
GO_0016324Cellular componentapical plasma membrane
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0016788Molecular functionhydrolase activity, acting on ester bonds
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0004046Molecular functionaminoacylase activity
GO_0046872Molecular functionmetal ion binding
GO_0003674Molecular functionmolecular_function

IV. Literature review

[source]
Gene nameACY3
Protein nameAminoacylase 3
N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) (EC 3.5.1.114) (Acylase III) (Aminoacylase-3) (ACY-3) (Aspartoacylase-2) (Hepatitis C virus core-binding protein 1) (HCBP1) (HCV core-binding protein 1)
SynonymsASPA2
DescriptionFUNCTION: Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity). .

AccessionsENST00000255082.8
Q96HD9
E9PRA7
ENST00000529256.1