Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell of proximal tubule | 8 studies | 54% ± 24% | |
| hepatocyte | 6 studies | 72% ± 18% | |
| endothelial cell | 3 studies | 20% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 23731.92 | 226 / 226 | 87% | 78.68 | 354 / 406 |
| kidney | 100% | 14499.75 | 89 / 89 | 82% | 53.34 | 740 / 901 |
| thymus | 97% | 23.40 | 632 / 653 | 0% | 0 | 0 / 605 |
| pancreas | 97% | 14.83 | 317 / 328 | 0% | 0 | 0 / 178 |
| adipose | 89% | 19.99 | 1066 / 1204 | 0% | 0 | 0 / 0 |
| adrenal gland | 87% | 9.39 | 224 / 258 | 0% | 0.06 | 1 / 230 |
| breast | 86% | 18.72 | 396 / 459 | 0% | 0 | 0 / 1118 |
| uterus | 81% | 10.92 | 137 / 170 | 0% | 0 | 0 / 459 |
| esophagus | 73% | 7.96 | 1061 / 1445 | 1% | 0.04 | 1 / 183 |
| intestine | 69% | 7.33 | 665 / 966 | 0% | 0.09 | 1 / 527 |
| stomach | 61% | 4.63 | 220 / 359 | 0% | 0 | 0 / 286 |
| prostate | 60% | 5.03 | 147 / 245 | 0% | 0 | 0 / 502 |
| lung | 57% | 5.14 | 331 / 578 | 0% | 0.02 | 1 / 1155 |
| bladder | 52% | 4.43 | 11 / 21 | 0% | 0 | 0 / 504 |
| ovary | 50% | 4.07 | 90 / 180 | 0% | 0 | 0 / 430 |
| spleen | 49% | 37.46 | 118 / 241 | 0% | 0 | 0 / 0 |
| skin | 40% | 3.69 | 730 / 1809 | 0% | 0 | 0 / 472 |
| blood vessel | 39% | 3.65 | 525 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 35% | 2.09 | 281 / 803 | 0% | 0 | 0 / 0 |
| heart | 34% | 2.49 | 297 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 31% | 12.91 | 285 / 929 | 0% | 0 | 0 / 0 |
| brain | 11% | 0.67 | 293 / 2642 | 0% | 0 | 0 / 705 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006633 | Biological process | fatty acid biosynthetic process |
| GO_0006805 | Biological process | xenobiotic metabolic process |
| GO_0006637 | Biological process | acyl-CoA metabolic process |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0015645 | Molecular function | fatty acid ligase activity |
| GO_0004321 | Molecular function | fatty-acyl-CoA synthase activity |
| GO_0031956 | Molecular function | medium-chain fatty acid-CoA ligase activity |
| GO_0102391 | Molecular function | decanoate-CoA ligase activity |
| GO_0016405 | Molecular function | CoA-ligase activity |
| GO_0018858 | Molecular function | benzoate-CoA ligase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | ACSM2B |
| Protein name | Acyl-coenzyme A synthetase ACSM2B, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 2B) (Benzoate--CoA ligase) (EC 6.2.1.25) (Butyrate--CoA ligase 2B) (Butyryl-coenzyme A synthetase 2B) (Middle-chain acyl-CoA synthetase 2B) (Xenobiotic/medium-chain fatty acid-CoA ligase HXM-A) medium-chain acyl-CoA ligase (EC 6.2.1.2) Acyl-CoA synthetase medium chain family member 2B |
| Synonyms | ACSM2 HYST1046 |
| Description | FUNCTION: Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism . Capable of activating medium-chain fatty acids (e.g. butyric (C4) to decanoic (C10) acids), and certain carboxylate-containing xenobiotics, e.g. benzoate . . |
| Accessions | ENST00000569163.1 ENST00000568098.1 ENST00000567288.5 ENST00000567001.5 Q68CK6 A0A087WU25 H3BP79 H3BRR3 H3BM61 H3BQ84 H3BNJ9 ENST00000568882.1 ENST00000566384.5 ENST00000569327.5 ENST00000565232.5 ENST00000329697.10 H3BTX9 ENST00000414188.6 ENST00000569344.5 ENST00000565322.5 H3BP39 |