ACSM2B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006633Biological processfatty acid biosynthetic process
GO_0006805Biological processxenobiotic metabolic process
GO_0006637Biological processacyl-CoA metabolic process
GO_0005759Cellular componentmitochondrial matrix
GO_0005739Cellular componentmitochondrion
GO_0015645Molecular functionfatty acid ligase activity
GO_0004321Molecular functionfatty-acyl-CoA synthase activity
GO_0031956Molecular functionmedium-chain fatty acid-CoA ligase activity
GO_0102391Molecular functiondecanoate-CoA ligase activity
GO_0016405Molecular functionCoA-ligase activity
GO_0018858Molecular functionbenzoate-CoA ligase activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameACSM2B
Protein nameAcyl-coenzyme A synthetase ACSM2B, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 2B) (Benzoate--CoA ligase) (EC 6.2.1.25) (Butyrate--CoA ligase 2B) (Butyryl-coenzyme A synthetase 2B) (Middle-chain acyl-CoA synthetase 2B) (Xenobiotic/medium-chain fatty acid-CoA ligase HXM-A)
medium-chain acyl-CoA ligase (EC 6.2.1.2)
Acyl-CoA synthetase medium chain family member 2B
SynonymsACSM2
HYST1046
DescriptionFUNCTION: Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism . Capable of activating medium-chain fatty acids (e.g. butyric (C4) to decanoic (C10) acids), and certain carboxylate-containing xenobiotics, e.g. benzoate . .

AccessionsENST00000569163.1
ENST00000568098.1
ENST00000567288.5
ENST00000567001.5
Q68CK6
A0A087WU25
H3BP79
H3BRR3
H3BM61
H3BQ84
H3BNJ9
ENST00000568882.1
ENST00000566384.5
ENST00000569327.5
ENST00000565232.5
ENST00000329697.10
H3BTX9
ENST00000414188.6
ENST00000569344.5
ENST00000565322.5
H3BP39