ACSF3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006633Biological processfatty acid biosynthetic process
GO_0090410Biological processmalonate catabolic process
GO_0006631Biological processfatty acid metabolic process
GO_0035338Biological processlong-chain fatty-acyl-CoA biosynthetic process
GO_0005654Cellular componentnucleoplasm
GO_0005759Cellular componentmitochondrial matrix
GO_0005739Cellular componentmitochondrion
GO_0016878Molecular functionacid-thiol ligase activity
GO_0090409Molecular functionmalonyl-CoA synthetase activity
GO_0005515Molecular functionprotein binding
GO_0031957Molecular functionvery long-chain fatty acid-CoA ligase activity
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameACSF3
Protein nameACSF3 protein
Malonate--CoA ligase ACSF3, mitochondrial (EC 6.2.1.76) (Acyl-CoA synthetase family member 3)
Acyl-CoA synthetase family member 3
SynonymsPSEC0197
DescriptionFUNCTION: Catalyzes the initial reaction in intramitochondrial fatty acid synthesis, by activating malonate and methylmalonate, but not acetate, into their respective CoA thioester . May have some preference toward very-long-chain substrates . .

AccessionsENST00000649953.1
ENST00000540697.5
F5H5A1
ENST00000538340.5
ENST00000541755.2
H0YGJ0
ENST00000535176.1
ENST00000537895.5
ENST00000406948.7
Q4G176
A0A3B3ISK9
H3BTS0
F5H2G6
H0YGC7
ENST00000614302.5
ENST00000378345.8
ENST00000542688.5
ENST00000537290.5
Q6P2C7
F5H3B2
F5GX20
F5H362
ENST00000543676.1
ENST00000317447.9
F5H755
ENST00000544543.5
H0YH37