I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| hepatocyte | 3 studies | 31% ± 16% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| hepatocyte | 3 studies | 31% ± 16% |
Insufficient scRNA-seq data for expression of ACOX2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 2150.36 | 653 / 653 | 97% | 29.38 | 587 / 605 |
| liver | 100% | 8704.87 | 225 / 226 | 92% | 66.07 | 373 / 406 |
| kidney | 100% | 2010.93 | 89 / 89 | 82% | 10.94 | 736 / 901 |
| intestine | 100% | 1780.53 | 965 / 966 | 75% | 12.61 | 397 / 527 |
| adrenal gland | 97% | 1347.75 | 249 / 258 | 79% | 15.87 | 181 / 230 |
| breast | 100% | 1137.80 | 457 / 459 | 71% | 24.51 | 794 / 1118 |
| ovary | 100% | 1350.49 | 180 / 180 | 61% | 5.86 | 262 / 430 |
| prostate | 99% | 1749.09 | 243 / 245 | 60% | 5.25 | 299 / 502 |
| brain | 69% | 266.25 | 1830 / 2642 | 76% | 7.60 | 537 / 705 |
| lung | 90% | 605.50 | 523 / 578 | 51% | 6.59 | 592 / 1155 |
| bladder | 95% | 1417.71 | 20 / 21 | 31% | 4.64 | 155 / 504 |
| stomach | 62% | 595.24 | 222 / 359 | 64% | 9.78 | 182 / 286 |
| uterus | 100% | 1761.99 | 170 / 170 | 19% | 2.01 | 86 / 459 |
| esophagus | 98% | 1268.21 | 1415 / 1445 | 15% | 1.07 | 28 / 183 |
| blood vessel | 100% | 1178.24 | 1330 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 100% | 1238.71 | 1198 / 1204 | 0% | 0 | 0 / 0 |
| skin | 78% | 556.05 | 1412 / 1809 | 21% | 2.80 | 101 / 472 |
| heart | 98% | 1270.72 | 842 / 861 | 0% | 0 | 0 / 0 |
| pancreas | 54% | 226.03 | 178 / 328 | 43% | 3.02 | 76 / 178 |
| muscle | 80% | 448.39 | 640 / 803 | 0% | 0 | 0 / 0 |
| spleen | 53% | 201.13 | 128 / 241 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 16% | 2.25 | 13 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.10 | 1 / 45 |
| peripheral blood | 1% | 5.63 | 13 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0055088 | Biological process | lipid homeostasis |
| GO_0006699 | Biological process | bile acid biosynthetic process |
| GO_0000038 | Biological process | very long-chain fatty acid metabolic process |
| GO_0033540 | Biological process | fatty acid beta-oxidation using acyl-CoA oxidase |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0005829 | Cellular component | cytosol |
| GO_0005777 | Cellular component | peroxisome |
| GO_0005782 | Cellular component | peroxisomal matrix |
| GO_0033791 | Molecular function | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity |
| GO_0016401 | Molecular function | palmitoyl-CoA oxidase activity |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0071949 | Molecular function | FAD binding |
| GO_0005504 | Molecular function | fatty acid binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0050660 | Molecular function | flavin adenine dinucleotide binding |
| Gene name | ACOX2 |
| Protein name | Acyl-coenzyme A oxidase Peroxisomal acyl-coenzyme A oxidase 2 (EC 1.17.99.3) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase) (Trihydroxycoprostanoyl-CoA oxidase) (THCA-CoA oxidase) (THCCox) Acyl-CoA oxidase 2 |
| Synonyms | |
| Description | FUNCTION: Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids . Capable of oxidizing short as well as long chain 2-methyl branched fatty acids (By similarity). . |
| Accessions | ENST00000302819.10 H7C573 ENST00000474098.1 ENST00000489472.1 Q99424 C9JY29 ENST00000460921.1 H7C4Y2 H7C4Q2 ENST00000459701.6 ENST00000492530.1 C9J0G0 |
