ACOT12 | OmnibusX

Name	Number of supported studies	Average coverage
hepatocyte	3 studies	45% ± 15%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of ACOT12 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	3213.88	226 / 226	89%	35.77	361 / 406
kidney	99%	95.07	88 / 89	4%	0.15	35 / 901
prostate	93%	16.35	229 / 245	1%	0.02	3 / 502
brain	78%	7.07	2068 / 2642	7%	0.13	46 / 705
bladder	81%	4.67	17 / 21	1%	0.02	3 / 504
breast	76%	4.41	349 / 459	0%	0.00	3 / 1118
skin	71%	4.17	1293 / 1809	4%	0.13	18 / 472
uterus	75%	5.16	127 / 170	0%	0.00	1 / 459
blood vessel	74%	4.03	991 / 1335	0%	0	0 / 0
intestine	70%	8.16	672 / 966	1%	0.08	3 / 527
adipose	68%	3.93	823 / 1204	0%	0	0 / 0
ovary	66%	3.09	118 / 180	0%	0	0 / 430
spleen	64%	6.61	154 / 241	0%	0	0 / 0
thymus	53%	2.24	343 / 653	10%	0.25	59 / 605
lung	56%	2.28	325 / 578	1%	0.04	12 / 1155
esophagus	56%	2.39	806 / 1445	1%	0.01	1 / 183
adrenal gland	54%	1.95	139 / 258	1%	0.02	2 / 230
stomach	46%	1.51	166 / 359	1%	0.02	2 / 286
pancreas	45%	1.41	146 / 328	0%	0	0 / 178
heart	42%	1.45	359 / 861	0%	0	0 / 0
peripheral blood	34%	3.82	315 / 929	0%	0	0 / 0
muscle	29%	0.81	230 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	10%	0.21	8 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006631	Biological process	fatty acid metabolic process
GO_0006637	Biological process	acyl-CoA metabolic process
GO_0006084	Biological process	acetyl-CoA metabolic process
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0045171	Cellular component	intercellular bridge
GO_0003986	Molecular function	acetyl-CoA hydrolase activity
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding
GO_0008289	Molecular function	lipid binding
GO_0052689	Molecular function	carboxylic ester hydrolase activity
GO_0005524	Molecular function	ATP binding

Gene name	ACOT12
Protein name	Acetyl-coenzyme A thioesterase (EC 3.1.2.1) (Acyl-CoA thioester hydrolase 12) (Acyl-coenzyme A thioesterase 12) (Acyl-CoA thioesterase 12) (Cytoplasmic acetyl-CoA hydrolase 1) (CACH-1) (hCACH-1) (START domain-containing protein 15) (StARD15)
Synonyms	CACH1 CACH STARD15
Description	FUNCTION: Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels . Preferentially hydrolyzes acetyl-CoA . .
Accessions	ENST00000307624.8 [Q8WYK0-1] Q8WYK0 ENST00000513751.1 [Q8WYK0-2]

ACOT12 report