Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell of lymphatic vessel | 4 studies | 26% ± 2% | |
| epithelial cell | 3 studies | 30% ± 5% | |
| mucus secreting cell | 3 studies | 23% ± 4% | |
| ciliated cell | 3 studies | 23% ± 6% | |
| type I pneumocyte | 3 studies | 21% ± 4% | |
| transit amplifying cell | 3 studies | 24% ± 8% |
Insufficient scRNA-seq data for expression of ABO at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 9342.63 | 653 / 653 | 94% | 31.34 | 570 / 605 |
| pancreas | 91% | 1749.91 | 298 / 328 | 83% | 19.10 | 147 / 178 |
| ovary | 98% | 8787.65 | 177 / 180 | 72% | 9.75 | 310 / 430 |
| lung | 92% | 2052.89 | 530 / 578 | 74% | 16.58 | 858 / 1155 |
| kidney | 100% | 4202.29 | 89 / 89 | 63% | 13.88 | 565 / 901 |
| intestine | 65% | 6740.80 | 631 / 966 | 93% | 35.02 | 490 / 527 |
| stomach | 72% | 1267.34 | 258 / 359 | 85% | 26.04 | 243 / 286 |
| bladder | 71% | 2436.57 | 15 / 21 | 69% | 16.83 | 350 / 504 |
| esophagus | 60% | 2686.01 | 862 / 1445 | 77% | 17.97 | 141 / 183 |
| adrenal gland | 100% | 6949.12 | 258 / 258 | 32% | 6.91 | 73 / 230 |
| uterus | 78% | 929.66 | 132 / 170 | 51% | 12.60 | 233 / 459 |
| prostate | 92% | 2139.02 | 226 / 245 | 28% | 3.13 | 141 / 502 |
| breast | 88% | 1068.40 | 406 / 459 | 19% | 2.44 | 217 / 1118 |
| ureter | 0% | 0 | 0 / 0 | 100% | 12.71 | 1 / 1 |
| adipose | 78% | 950.01 | 937 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 67% | 13.20 | 30 / 45 |
| skin | 62% | 856.13 | 1122 / 1809 | 0% | 0.03 | 2 / 472 |
| spleen | 59% | 546.81 | 143 / 241 | 0% | 0 | 0 / 0 |
| heart | 50% | 459.25 | 430 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 7% | 63.98 | 100 / 1335 | 0% | 0 | 0 / 0 |
| brain | 4% | 31.22 | 114 / 2642 | 0% | 0.02 | 2 / 705 |
| liver | 0% | 3.79 | 1 / 226 | 3% | 0.38 | 13 / 406 |
| peripheral blood | 2% | 13.76 | 18 / 929 | 0% | 0 | 0 / 0 |
| muscle | 1% | 8.53 | 10 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0005975 | Biological process | carbohydrate metabolic process |
| GO_0030259 | Biological process | lipid glycosylation |
| GO_0006486 | Biological process | protein glycosylation |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0032580 | Cellular component | Golgi cisterna membrane |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0031982 | Cellular component | vesicle |
| GO_0030145 | Molecular function | manganese ion binding |
| GO_0004381 | Molecular function | fucosylgalactoside 3-alpha-galactosyltransferase activity |
| GO_0003823 | Molecular function | antigen binding |
| GO_0004380 | Molecular function | glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity |
| GO_0000166 | Molecular function | nucleotide binding |
| Gene name | ABO |
| Protein name | ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase) ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase) (ABO glycosyltransferase) A1-specific alpha 1-3-N-acetylgalactosaminyltransferase A blood group antigen ABO-glycosyltransferase B Ax glycosyltransferase ABO glycotransferase (EC 2.4.1.40) Histo-blood group ABO system transferase (EC 2.4.1.40) ABO antigen (B antigen) ABO glycosyltransferase (Alpha 1-3-galactosyltransferase) ABO antigen (ABO glycosyltransferase) ABO blood group transferase A ABO protein ABO alpha 1-3 galactosyltransferase (EC 2.4.1.37) B(A) glycosyltransferase Alpha-1,3-N-acetylgalactosaminyltransferase ABO glycosyltransferase (Bw glycosyltransferase) ABO glycosyltransferase Ael B(A)-specific glycosyltransferase B antigen N-terminal truncated ABO glycosyltransferase B-specific 1-3-galactosyltransferase variant 1 (EC 2.4.1.37) ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase) Alpha-3-galactosylaminyltransferase (EC 2.4.1.40) (Alpha-3-galactosyltransferase (EC 2.4.1.37)) Aint glycosyltransferase ABO blood group exon4 Cis ABO5 glycosyltransferase ABO glycosyltransferase (Transferase A) Histo-blood group ABO system transferase ABO glycosyltransferase (Truncated alpha-3-galactosyltransferase) Bx glycosyltransferase B-specific alpha 1-3-galactosyltransferase (EC 2.4.1.37) Truncated glycosyltransferase ABO weak transfer variant ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) Alpha-3-galactosyltransferase (EC 2.4.1.37) Histo-blood group A2 transferase CisAB glycosyltransferase ABO glycosyltransferase A antigen ABO glycosyltransferase (Alpha-1,3-N-acetylgalactosaminyltransferase) (Alpha-1,3-galactosyltransferase) Non-functional ABO glycosyltransferase Alpha 1-3-galactosyltransferase (EC 2.4.1.87) ABO transferase GTB ABO glycotransferase ABO antigen (B-specific alpha 1-3-galactosyltransferase) ABO glycocyltransferase (ABO glycosyltransferase) (Blood group antigen) (Truncated ABO blood group protein) (Truncated glycosyltransferase) ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) (ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase)) (B3 antigen) (Bel antigen) ABO glycosyltransferase (Alpha 1-3-N-acetylgalactosaminyltransferase) (Variant glycosyltransferase A) A transferase Glycosyltransferase A Bm glycosyltransferase Glycosyltransferase B Glycosyltransferase A (EC 2.4.1.40) A transferase (ABO blood group glycosyltransferase B) (B transferase) (B(A) glycosyltransferase) ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase) (ABO glycosyltransferase) ABO blood group antigen ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Glycosyltransferase A (Histo-blood group ABO system transferase) ABO A3 transferase variant GTA ABO antigen (B-specific alpha 1->3 galactosyltransferase) Ax transferase (Glycosyltransferase A) ABO glycosyltransferase (Alpha 1-3-N-acetylgactosaminyltransferase) (Histo-blood group protein) ABO blood group transferase B (ABO glycosyltransferase) Alpha-3-galactosylaminyltransferase (EC 2.4.1.40) ABO blood group protein A1-specific alpha 1->3 N-acetylgalactosaminyltransferase Alpha 1-3-galactosyltransferase ABO glycosyltransferase ABO glycosyltransferase variant B Ael glycosyltransferase (EC 2.4.1.40) ABO glycosyltransferase B antigen Glycosyltransferase B (EC 2.4.1.37) Fucosylglycoprotein ABO blood group transferase B Ael glycosyltransferase Alpha-3-galactosylaminyltransferase Histo-blood group ABO system transferase (Fucosylglycoprotein 3-alpha-galactosyltransferase) (Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase) (Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase) (EC 2.4.1.40) (Glycoprotein-fucosylgalactoside alpha-galactosyltransferase) (EC 2.4.1.37) (Histo-blood group A transferase) (A transferase) (Histo-blood group B transferase) (B transferase) (NAGAT) [Cleaved into: Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form] A Glycosyltranserase Alpha 1-3-N-acetylgactosaminyltransferase (Glycosyltransferase A (EC 2.4.1.40)) ABO blood group (ABO glycosyltransferase) A Transferase Ax transferase ABO blood group A antigen Ax-specific alpha 1->3 N-acetylgalactosaminyltransferase A3-specific alpha 1->3 N-acetylgalactosaminyltransferase ABO variant A B(A)-specific alpha 1->3 galactosyltransferase A-transferase Alpha 1-3-N-acetylgalactosaminyltransferase (EC 2.4.1.40) A2-specific alpha 1->3 N-acetylgalactosaminyltransferase Glycosyltransferase Aw glycosyltransferase ABO blood group protein (ABO transferase) Alpha 1-3-N-acetylgalactosaminyltransferase Cis-AB glycosyltransferase ABO glycosyltransferase (ABO-glycosyltransferase B) ABO glycosyltransferase variant Transferase Alpha 1-3-galactosyltransferase (EC 2.4.1.37) ABO blood group Alpha 1-3-N-acetylgalactosaminyltransferase (B(A) glycosyltransferase) ABO blood group B antigen (ABO glycosyltransferase) ABO glycosyltransferase (B antigen) (Bel antigen) (Bw glycosyltransferases) (Transferase B, alpha 1-3-galactosyltransferase) B3-specific alpha 1->3 galactosyltransferase Alpha 1-3-N-acetylgactosaminyltransferase O-specific alpha 1->3 N-acetylgalactosaminyltransferase Cis-AB-specific alpha 1->3 N-acetylgalactosaminyltransferase A antigen ABO blood group glycosyltransferase B (GTB) A antigen (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase) GTA (Glycosyltransferase) ABO blood group protein (Glycosyltransferase) (ABO protein) (Alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase) (Histo blood group ABO glycosyltransferase) Truncated ABO glycosyltransferase |
| Synonyms | |
| Description | FUNCTION: This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. |
| Accessions | X2J925 E3T388 A0A0K2FRI0 A5X6H7 U5YJZ4 B5TRS7 X5M235 U5YMY3 Q9UMY6 Q99483 C3VA47 Q6R5A7 Q9C090 A0A0U4BH10 Q679L5 A0A0B5JAH3 I6U2M5 V5UU28 W0LH19 Q70V32 I1VYG6 A0A060VGH1 F0X353 Q45L90 Q8WXY9 V9GWR4 A1Z626 V9GWR7 V9GWR6 A0A2H4ZEV1 A0A411HQW3 A0A5J6NBQ0 A0A1S6Q3Z4 A0A1U9XQJ1 Q70V16 W0LGR6 E3TGS0 Q9UK42 Q99488 J9XT30 A0A0F6RA81 A0A3G8GDZ7 A0A411JJA3 A5X6H4 ENST00000611156.4 Q9UIR1 C6KD89 F0X360 A0A1A9C9H0 Q9UQ65 D3HIC2 Q8WXZ3 Q2PJQ0 A0A7S9GFL1 B1AC83 Q70V31 Q8WXY6 E3T202 A0A1A9C8N6 A0A1S6KKE7 A0A068F7M1 V5ZDN9 A0A5J6DKG6 A0A8E8U6B6 A0A0A7RCH0 Q6L641 X2GB60 A9QUS2 C3VA42 Q4VVG1 A0A0K0WRU2 A0A1I9WVP6 B0FY49 C6KIE4 Q7Z535 Q2PJQ1 ENST00000538324.2 U5YKX4 C5J4L4 A0A6G5XP74 Q70V35 D3HIC4 Q9UMY7 Q8WXZ2 Q8WXZ1 Q8NFW0 A0A5J6Y043 A0A411PBV5 G3FEP9 A0A221C5L4 Q6L644 Q70V30 Q6L636 Q2LFC6 Q9UBW4 E3T204 A9UHN4 A0A060VHY2 C6KIE5 A0A5J6DCC3 U5NNJ6 Q5VJ25 A0A411PBQ3 B2CW70 U5YK38 Q99481 Q8WXZ0 J9XV13 C6KD92 A0A0U2M389 A0A7L9QHV6 Q9NY02 A0A286RTX0 Q9UMY8 V5UUM3 A0AA51NGK4 Q70V13 B2CPK1 A0A2D1QUU1 E3T205 U5YN54 A0A068B0Y9 Q4JGX1 A0A1A9C7R9 Q9C087 D8MIB8 H9XVR5 Q538Y8 C1K0H8 Q70V10 I6TS22 C3VA43 A8E057 B0B1U2 Q9UP69 E3T201 Q8WXY5 Q9UQ62 Q2LFC5 Q70V12 A0A7P0TA91 Q3ZMG8 Q4VY24 E3T206 Q99480 A0A7L9QHJ7 Q4JGX2 Q207T9 Q70V15 G0V4X4 Q6IS73 A0A6M6AM23 U5NJV0 Q6R675 B8Y570 A0A0B5JHW3 B2CPK0 C6KD90 A0A1A9C9H5 A1EAJ6 Q2VU70 Q15951 Q70V29 Q8WXY8 O15512 A0A0D3RYQ2 A0AA50L304 Q8WXZ7 W6JLF7 A0A8E8PHN1 V5UV59 C6KD91 B5LYM4 Q2PJQ2 D8MIB7 A0A4P8PNL3 Q9C088 Q8WXZ6 A0A089QDC1 A0A087X009 A0A1A9C8N0 A5X6H5 Q56S55 A0A1A9C7A3 A0A023W307 V5ZDN8 A0A0A0RW37 J9XP05 Q6L647 Q56S53 A0A0S3J407 A0A481N0Z6 D3HIC3 A0AA49QAS5 Q70V39 A0A7H1D390 A0A023W2C2 B0LVD8 E3TGS1 E3T200 U5NNF6 A0A0A1TJL0 A0A0S1S772 Q70V41 F2X1S4 A0A7D5PXH6 I1VEE1 Q6L639 Q9BQ97 A0A060VD92 Q8WXZ4 B0FY48 A0A897TGC5 U5NKB0 G8IIL0 A0A7T0BRL2 A0AA50L2Y1 M9QZC0 Q6L640 F0X363 B6E948 G9HR99 Q99482 E3T203 A0A097DCZ8 A0A0B5JFG5 A0A6B9IJI4 E1Y3Y7 A0A0N7FMT7 Q8WWJ1 A0A088MFT4 K4MQF1 A0A5J6XWN0 Q70V24 A0A248X8V7 A0A1A9C7B2 Q9NPA6 Q70V25 Q9UQ63 Q56S52 A0A7S9YYE8 Q6PNN6 O14759 A0A7S8FK17 Q6L635 A0A0S3J4Y2 A0A1W5VPF1 Q99477 V5ZDU6 A0A7G5VVT0 A0A2P1M8M7 A0A1Q1PRB1 Q7LCZ1 A0A1A9C7R4 E5L3Z6 A0A023J8Y7 V9GWR5 V5ZDU5 A0A2Z4FS35 A8D971 Q8WXY7 A0A2H4ZEU8 Q67BB2 D7RNR0 A0A087X0C2 A8E058 E3TGR9 A0A2D3E298 K4MTH0 Q99486 A0A346SCL3 A0A0K2FSH1 U5YJY7 H6UK82 Q70V22 Q9UQ66 I6SWF8 Q70V33 A0A0A8WK19 C3VA45 ENST00000679909.1 Q4LAQ2 Q2VU69 Q56S51 Q70V26 Q99478 Q99479 A5X6H8 A0A3G8GE08 A0A6C6XEK5 Q538Y9 E1Y3Y6 C3VA44 Q9UQ67 A0A7D5HSY5 A5X6H3 F0X359 A9UHN3 Q9C089 Q6LCV2 Q4JGX0 A5X6H9 G3FM75 E3T387 Q6L637 Q6R5J3 H6UK83 D3YE67 A0A1J0M5B7 Q45L91 Q9UP70 A0A0G3VPC9 Q2PJQ3 H6UK81 Q1L131 Q8WXZ5 H6A2X0 Q102J2 A0A346RV53 Q6L638 Q6L643 H6VPB4 A0A2U8QPH3 F0X357 A0A4Y5QRQ9 A0A5J6CXZ0 T1WHV8 B0FY45 E0ZMB5 B0FY46 K4INT6 A0A1A9C8T9 Q70V37 P16442 V5USW5 F0X364 A0A4Y5N0E3 B6E949 K4MMM0 Q9UQ64 A0A0A1TST4 A0A8A2IED2 J9XP21 Q8N3W8 A0A1A9C8U5 I7APP0 V5ZDP0 Q6L645 Q6L648 |
