ABHD4 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of ABHD4 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	4254.64	1445 / 1445	100%	53.33	183 / 183
thymus	100%	3887.57	653 / 653	100%	44.46	603 / 605
prostate	100%	3347.61	245 / 245	100%	35.74	500 / 502
ovary	100%	2254.30	180 / 180	100%	44.68	428 / 430
skin	100%	3184.82	1808 / 1809	99%	38.65	469 / 472
kidney	100%	3663.54	89 / 89	99%	35.78	894 / 901
lung	100%	3003.78	578 / 578	99%	49.56	1146 / 1155
breast	100%	3066.33	459 / 459	99%	41.23	1105 / 1118
liver	100%	1977.64	226 / 226	98%	31.18	398 / 406
brain	98%	1547.68	2589 / 2642	100%	83.94	704 / 705
uterus	100%	4153.42	170 / 170	98%	42.08	449 / 459
stomach	100%	3197.52	359 / 359	98%	27.95	279 / 286
bladder	100%	4069.19	21 / 21	97%	33.40	491 / 504
adrenal gland	100%	4566.09	258 / 258	97%	37.14	224 / 230
pancreas	98%	1356.73	321 / 328	99%	40.25	177 / 178
intestine	100%	2830.19	966 / 966	97%	24.90	509 / 527
adipose	100%	3456.02	1204 / 1204	0%	0	0 / 0
blood vessel	100%	4898.00	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	54.99	80 / 80
spleen	100%	2423.83	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	42.23	45 / 45
ureter	0%	0	0 / 0	100%	10.93	1 / 1
peripheral blood	99%	2540.80	917 / 929	0%	0	0 / 0
muscle	99%	2009.71	792 / 803	0%	0	0 / 0
heart	95%	1804.47	819 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	93%	16.45	27 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0006654	Biological process	phosphatidic acid biosynthetic process
GO_0070292	Biological process	N-acylphosphatidylethanolamine metabolic process
GO_0055088	Biological process	lipid homeostasis
GO_0036152	Biological process	phosphatidylethanolamine acyl-chain remodeling
GO_0016042	Biological process	lipid catabolic process
GO_0005811	Cellular component	lipid droplet
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0005739	Cellular component	mitochondrion
GO_0004622	Molecular function	lysophospholipase activity
GO_0016787	Molecular function	hydrolase activity
GO_0005515	Molecular function	protein binding
GO_0042171	Molecular function	lysophosphatidic acid acyltransferase activity

Gene name	ABHD4
Protein name	(Lyso)-N-acylphosphatidylethanolamine lipase (EC 3.1.1.-) (Alpha/beta hydrolase domain-containing protein 4) (Abhydrolase domain-containing protein 4) (Alpha/beta-hydrolase 4) Abhydrolase domain containing 4, N-acyl phospholipase B
Synonyms
Description	FUNCTION: Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine. .
Accessions	ENST00000428304.7 [Q8TB40-1] F5H067 H0YFD5 ENST00000541962.1 ENST00000537243.5 ENST00000542041.1 F5GZC9 J3KMW0 ENST00000216327.10 ENST00000545034.5 F5H6T0 ENST00000418446.6 [Q8TB40-2] Q8TB40

ABHD4 report