Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 11 studies | 34% ± 14% | |
| epithelial cell | 11 studies | 33% ± 17% | |
| goblet cell | 4 studies | 21% ± 3% | |
| secretory cell | 4 studies | 29% ± 13% | |
| abnormal cell | 3 studies | 18% ± 2% | |
| intestinal crypt stem cell | 3 studies | 21% ± 4% |
Insufficient scRNA-seq data for expression of ABHD11 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 3796.81 | 653 / 653 | 100% | 75.30 | 604 / 605 |
| prostate | 100% | 3078.46 | 245 / 245 | 99% | 114.09 | 499 / 502 |
| breast | 100% | 1601.06 | 459 / 459 | 99% | 84.25 | 1105 / 1118 |
| pancreas | 100% | 1627.78 | 328 / 328 | 98% | 61.47 | 175 / 178 |
| intestine | 100% | 2066.63 | 966 / 966 | 98% | 119.13 | 518 / 527 |
| bladder | 100% | 967.14 | 21 / 21 | 98% | 79.59 | 494 / 504 |
| kidney | 100% | 3158.88 | 89 / 89 | 98% | 78.59 | 880 / 901 |
| stomach | 99% | 663.23 | 356 / 359 | 98% | 92.31 | 279 / 286 |
| lung | 99% | 1146.99 | 573 / 578 | 97% | 60.20 | 1117 / 1155 |
| uterus | 99% | 733.72 | 169 / 170 | 95% | 56.32 | 437 / 459 |
| esophagus | 100% | 789.39 | 1438 / 1445 | 93% | 53.38 | 170 / 183 |
| brain | 99% | 910.70 | 2620 / 2642 | 92% | 26.46 | 652 / 705 |
| ovary | 92% | 395.19 | 165 / 180 | 100% | 126.25 | 429 / 430 |
| skin | 100% | 1103.16 | 1808 / 1809 | 88% | 28.38 | 414 / 472 |
| adrenal gland | 100% | 1111.76 | 258 / 258 | 82% | 23.90 | 189 / 230 |
| liver | 100% | 706.22 | 226 / 226 | 58% | 20.40 | 235 / 406 |
| spleen | 100% | 1060.98 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 103.86 | 1 / 1 |
| adipose | 99% | 657.79 | 1192 / 1204 | 0% | 0 | 0 / 0 |
| heart | 98% | 987.80 | 842 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 98% | 529.31 | 1303 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 95% | 26.89 | 76 / 80 |
| muscle | 90% | 436.66 | 722 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 89% | 41.86 | 40 / 45 |
| peripheral blood | 86% | 498.12 | 798 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 62% | 14.93 | 18 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0044255 | Biological process | cellular lipid metabolic process |
| GO_0008150 | Biological process | biological_process |
| GO_0005575 | Cellular component | cellular_component |
| GO_0045252 | Cellular component | oxoglutarate dehydrogenase complex |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0016298 | Molecular function | lipase activity |
| GO_0052689 | Molecular function | carboxylic ester hydrolase activity |
| GO_0003674 | Molecular function | molecular_function |
| Gene name | ABHD11 |
| Protein name | sn-1-specific diacylglycerol lipase ABHD11 (EC 3.1.1.116) (Alpha/beta hydrolase domain-containing protein 11) sn-1-specific diacylglycerol lipase ABHD11 (EC 3.1.1.116) (Alpha/beta hydrolase domain-containing protein 11) (Abhydrolase domain-containing protein 11) (Williams-Beuren syndrome chromosomal region 21 protein) Abhydrolase domain containing 11 |
| Synonyms | PP1226 WBSCR21 |
| Description | FUNCTION: Catalyzes the hydrolysis of diacylglycerol in vitro and may function as a key regulator in lipid metabolism, namely by regulating the intracellular levels of diacylglycerol . 1,2-diacyl-sn-glycerols are the preferred substrate over 1,3-diacyl-sn-glycerols (By similarity). The enzyme hydrolyzes stearate in preference to palmitate from the sn-1 position of 1,2-diacyl-sn-glycerols (By similarity). Maintains the functional lipoylation of the 2-oxoglutarate dehydrogenase complex (OGDHc) through its interaction with the OGDHc by preventing the formation of lipoyl adducts . In addition, is also required for the expansion and differentiation of embryonic stem cells (ESCs) (By similarity). . |
| Accessions | ENST00000437891.5 C9J7Q4 H7BZ58 H7C396 ENST00000412965.5 ENST00000437775.7 [Q8NFV4-4] ENST00000222800.8 [Q8NFV4-1] Q8NFV4 ENST00000357419.9 [Q8NFV4-2] ENST00000395147.9 [Q8NFV4-6] H0YC52 ENST00000474130.1 ENST00000458339.6 |
