ABCB8 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0140141Biological processmitochondrial potassium ion transmembrane transport
GO_0006884Biological processcell volume homeostasis
GO_0015833Biological processpeptide transport
GO_0071805Biological processpotassium ion transmembrane transport
GO_0055085Biological processtransmembrane transport
GO_0043190Cellular componentATP-binding cassette (ABC) transporter complex
GO_0031966Cellular componentmitochondrial membrane
GO_0005730Cellular componentnucleolus
GO_0005654Cellular componentnucleoplasm
GO_0062157Cellular componentmitochondrial ATP-gated potassium channel complex
GO_0016020Cellular componentmembrane
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005739Cellular componentmitochondrion
GO_0015440Molecular functionABC-type peptide transporter activity
GO_0005515Molecular functionprotein binding
GO_0016887Molecular functionATP hydrolysis activity
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameABCB8
Protein nameATP binding cassette subfamily B member 8
ATP binding cassette subfamily B member 8 (ATP-binding cassette, sub-family B (MDR/TAP), member 8, isoform CRA_c)
Mitochondrial potassium channel ATP-binding subunit (ATP-binding cassette sub-family B member 8, mitochondrial) (ABCB8) (Mitochondrial ATP-binding cassette 1) (M-ABC1) (Mitochondrial sulfonylurea-receptor) (MITOSUR)
Alternative protein ABCB8
SynonymsMABC1
hCG_18685
MITOSUR
DescriptionFUNCTION: ATP-binding subunit of the mitochondrial potassium channel located in the mitochondrial inner membrane . Together with CCDC51/MITOK, forms a protein complex localized in the mitochondria that mediates ATP-dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel) . Plays a role in mitochondrial iron transport . Required for maintenance of normal cardiac function, possibly by influencing mitochondrial iron export and regulating the maturation of cytosolic iron sulfur cluster-containing enzymes (By similarity). .

AccessionsC9JA03
ENST00000466514.5
L8EAK9
ENST00000482309.5
ENST00000491920.1
ENST00000477719.5
ENST00000542328.5 [Q9NUT2-4]
ENST00000297504.10 [Q9NUT2-1]
ENST00000461373.5
ENST00000498578.5 [Q9NUT2-3]
F2Z2Z1
ENST00000489192.5
H7C5K9
ENST00000470645.5
ENST00000358849.9 [Q9NUT2-2]
C9JTY4
C9JYI3
ENST00000488551.5
F2Z3G8
ENST00000477092.5
F8WC43
Q9NUT2