AADAC | OmnibusX

Name	Number of supported studies	Average coverage
enterocyte	6 studies	39% ± 9%	Explore
hepatocyte	4 studies	47% ± 15%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of AADAC at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	7684.24	226 / 226	96%	420.64	388 / 406
pancreas	98%	1510.06	322 / 328	73%	18.52	130 / 178
adrenal gland	100%	16069.98	258 / 258	25%	17.91	57 / 230
stomach	68%	712.30	243 / 359	37%	10.15	106 / 286
lung	44%	149.83	256 / 578	47%	16.75	541 / 1155
adipose	69%	427.63	833 / 1204	0%	0	0 / 0
skin	65%	266.86	1180 / 1809	2%	0.67	9 / 472
breast	63%	351.17	289 / 459	3%	1.19	33 / 1118
ovary	2%	5.22	4 / 180	55%	7.75	235 / 430
esophagus	11%	16.73	156 / 1445	46%	14.90	84 / 183
bladder	19%	32.33	4 / 21	30%	18.00	153 / 504
intestine	15%	344.68	149 / 966	20%	6.55	104 / 527
tonsil	0%	0	0 / 0	16%	3.21	7 / 45
uterus	2%	3.37	4 / 170	13%	1.47	58 / 459
thymus	7%	8.76	46 / 653	0%	0.01	1 / 605
heart	5%	15.72	46 / 861	0%	0	0 / 0
peripheral blood	2%	4.20	15 / 929	0%	0	0 / 0
blood vessel	1%	3.68	18 / 1335	0%	0	0 / 0
spleen	1%	16.65	3 / 241	0%	0	0 / 0
kidney	0%	0	0 / 89	1%	0.25	9 / 901
prostate	0%	0.48	1 / 245	0%	0	0 / 502
brain	0%	0.39	2 / 2642	0%	0	0 / 705
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006805	Biological process	xenobiotic metabolic process
GO_0006629	Biological process	lipid metabolic process
GO_0010898	Biological process	positive regulation of triglyceride catabolic process
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0004806	Molecular function	triglyceride lipase activity
GO_0016298	Molecular function	lipase activity
GO_0017171	Molecular function	serine hydrolase activity
GO_0019213	Molecular function	deacetylase activity
GO_0003824	Molecular function	catalytic activity
GO_0005515	Molecular function	protein binding

Gene name	AADAC
Protein name	Arylacetamide deacetylase (EC 3.1.1.3) Arylacetamide deacetylase
Synonyms	DAC
Description	FUNCTION: Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly. Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity. .
Accessions	C9K0E9 ENST00000488869.1 P22760 ENST00000232892.12

AADAC report