Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| adipocyte | 9 studies | 31% ± 12% | |
| glutamatergic neuron | 8 studies | 36% ± 23% | |
| epithelial cell | 5 studies | 26% ± 9% | |
| retinal ganglion cell | 4 studies | 42% ± 18% | |
| GABAergic neuron | 4 studies | 38% ± 14% | |
| goblet cell | 4 studies | 29% ± 17% | |
| endothelial cell | 3 studies | 28% ± 1% | |
| transit amplifying cell | 3 studies | 21% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 34% ± 18% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 99% | 2667.41 | 1437 / 1445 | 100% | 11.24 | 183 / 183 |
| prostate | 100% | 1604.35 | 244 / 245 | 100% | 11.35 | 501 / 502 |
| breast | 100% | 4373.39 | 458 / 459 | 100% | 12.95 | 1113 / 1118 |
| uterus | 99% | 1331.39 | 169 / 170 | 100% | 10.83 | 457 / 459 |
| thymus | 100% | 1623.91 | 650 / 653 | 99% | 7.56 | 599 / 605 |
| bladder | 100% | 1248.24 | 21 / 21 | 98% | 8.70 | 495 / 504 |
| stomach | 99% | 1909.80 | 355 / 359 | 99% | 9.47 | 284 / 286 |
| intestine | 98% | 1710.02 | 951 / 966 | 100% | 10.85 | 525 / 527 |
| pancreas | 97% | 1443.40 | 319 / 328 | 100% | 9.63 | 178 / 178 |
| ovary | 100% | 1304.63 | 180 / 180 | 97% | 6.60 | 417 / 430 |
| skin | 99% | 5781.95 | 1799 / 1809 | 95% | 6.29 | 448 / 472 |
| kidney | 99% | 1493.61 | 88 / 89 | 95% | 6.04 | 859 / 901 |
| lung | 92% | 1295.75 | 529 / 578 | 100% | 9.87 | 1152 / 1155 |
| adrenal gland | 98% | 1460.83 | 253 / 258 | 92% | 7.70 | 212 / 230 |
| brain | 90% | 1919.53 | 2386 / 2642 | 99% | 5.70 | 695 / 705 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 16.69 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.21 | 1 / 1 |
| adipose | 100% | 3956.25 | 1202 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 98% | 1087.28 | 236 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 6.19 | 28 / 29 |
| eye | 0% | 0 | 0 / 0 | 93% | 4.46 | 74 / 80 |
| blood vessel | 92% | 1003.91 | 1233 / 1335 | 0% | 0 | 0 / 0 |
| liver | 32% | 298.27 | 73 / 226 | 58% | 3.18 | 237 / 406 |
| heart | 85% | 938.56 | 728 / 861 | 0% | 0 | 0 / 0 |
| muscle | 41% | 321.64 | 332 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 27% | 784.75 | 247 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0046951 | Biological process | ketone body biosynthetic process |
| GO_0006631 | Biological process | fatty acid metabolic process |
| GO_0032024 | Biological process | positive regulation of insulin secretion |
| GO_0005829 | Cellular component | cytosol |
| GO_0030729 | Molecular function | acetoacetate-CoA ligase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | AACS |
| Protein name | Acetoacetyl-CoA synthetase (EC 6.2.1.16) AACS protein Acetoacetyl-CoA synthetase (EC 6.2.1.16) (Acyl-CoA synthetase family member 1) (Protein sur-5 homolog) Alternative protein AACS Acetoacetyl-CoA synthetase |
| Synonyms | ACSF1 |
| Description | FUNCTION: Converts acetoacetate to acetoacetyl-CoA in the cytosol (By similarity). Ketone body-utilizing enzyme, responsible for the synthesis of cholesterol and fatty acids (By similarity). . FUNCTION: Converts acetoacetate to acetoacetyl-CoA in the cytosol. . |
| Accessions | E7EW25 A0A5A4UB59 Q86V21 ENST00000418937.6 L8ECK1 ENST00000316519.11 [Q86V21-1] Q49AJ4 |
