Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 28% ± 8% |
Insufficient scRNA-seq data for expression of AAAS at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adrenal gland | 100% | 5352.29 | 258 / 258 | 100% | 35.07 | 230 / 230 |
| esophagus | 100% | 3392.34 | 1445 / 1445 | 100% | 26.99 | 183 / 183 |
| liver | 100% | 1866.73 | 226 / 226 | 100% | 22.86 | 406 / 406 |
| ovary | 100% | 3248.87 | 180 / 180 | 100% | 41.10 | 430 / 430 |
| prostate | 100% | 3678.04 | 245 / 245 | 100% | 33.43 | 502 / 502 |
| thymus | 100% | 3528.18 | 653 / 653 | 100% | 31.47 | 605 / 605 |
| uterus | 100% | 3658.12 | 170 / 170 | 100% | 36.26 | 459 / 459 |
| skin | 100% | 2524.34 | 1808 / 1809 | 100% | 36.30 | 472 / 472 |
| kidney | 100% | 3089.98 | 89 / 89 | 100% | 27.26 | 900 / 901 |
| intestine | 100% | 3360.24 | 966 / 966 | 100% | 32.77 | 526 / 527 |
| bladder | 100% | 3277.38 | 21 / 21 | 100% | 31.34 | 503 / 504 |
| lung | 100% | 2412.63 | 577 / 578 | 100% | 29.32 | 1154 / 1155 |
| pancreas | 100% | 1868.20 | 327 / 328 | 100% | 25.79 | 178 / 178 |
| stomach | 100% | 2684.16 | 359 / 359 | 100% | 30.06 | 285 / 286 |
| breast | 100% | 2846.39 | 459 / 459 | 100% | 30.69 | 1114 / 1118 |
| brain | 99% | 1893.38 | 2627 / 2642 | 100% | 36.17 | 705 / 705 |
| adipose | 100% | 2612.33 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 40.00 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 40.44 | 29 / 29 |
| spleen | 100% | 3325.30 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 32.72 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 24.55 | 1 / 1 |
| blood vessel | 100% | 3135.55 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 99% | 1850.50 | 798 / 803 | 0% | 0 | 0 / 0 |
| heart | 98% | 2061.67 | 846 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 91% | 1516.58 | 842 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0051028 | Biological process | mRNA transport |
| GO_0007612 | Biological process | learning |
| GO_0046822 | Biological process | regulation of nucleocytoplasmic transport |
| GO_0090307 | Biological process | mitotic spindle assembly |
| GO_0009566 | Biological process | fertilization |
| GO_0006913 | Biological process | nucleocytoplasmic transport |
| GO_0015031 | Biological process | protein transport |
| GO_0001578 | Biological process | microtubule bundle formation |
| GO_0005643 | Cellular component | nuclear pore |
| GO_0000922 | Cellular component | spindle pole |
| GO_0072686 | Cellular component | mitotic spindle |
| GO_0016020 | Cellular component | membrane |
| GO_0005813 | Cellular component | centrosome |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005635 | Cellular component | nuclear envelope |
| GO_0005829 | Cellular component | cytosol |
| GO_0031965 | Cellular component | nuclear membrane |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| GO_0003674 | Molecular function | molecular_function |
| Gene name | AAAS |
| Protein name | Mutant Allgrove syndrome protein Aladin (Adracalin) Aladin WD repeat nucleoporin |
| Synonyms | GL003 ADRACALA |
| Description | FUNCTION: Plays a role in the normal development of the peripheral and central nervous system . Required for the correct localization of aurora kinase AURKA and the microtubule minus end-binding protein NUMA1 as well as a subset of AURKA targets which ensures proper spindle formation and timely chromosome alignment . . |
| Accessions | F8VZ44 ENST00000548931.6 ENST00000547757.2 ENST00000708962.1 [Q9NRG9-2] Q9NRG9 ENST00000394384.7 [Q9NRG9-2] D9DBT2 ENST00000708963.1 [Q9NRG9-1] D9DBT0 H3BU82 D9DBT1 F8VUB6 D9DBS9 ENST00000550286.5 ENST00000209873.9 [Q9NRG9-1] D9DBT3 |