AAAS report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of AAAS at tissue level.

III. Associated gene sets

GO_0051028Biological processmRNA transport
GO_0007612Biological processlearning
GO_0046822Biological processregulation of nucleocytoplasmic transport
GO_0090307Biological processmitotic spindle assembly
GO_0009566Biological processfertilization
GO_0006913Biological processnucleocytoplasmic transport
GO_0015031Biological processprotein transport
GO_0001578Biological processmicrotubule bundle formation
GO_0005643Cellular componentnuclear pore
GO_0000922Cellular componentspindle pole
GO_0072686Cellular componentmitotic spindle
GO_0016020Cellular componentmembrane
GO_0005813Cellular componentcentrosome
GO_0005654Cellular componentnucleoplasm
GO_0005635Cellular componentnuclear envelope
GO_0005829Cellular componentcytosol
GO_0031965Cellular componentnuclear membrane
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding
GO_0003674Molecular functionmolecular_function

IV. Literature review

[source]
Gene nameAAAS
Protein nameMutant Allgrove syndrome protein
Aladin (Adracalin)
Aladin WD repeat nucleoporin
SynonymsGL003
ADRACALA
DescriptionFUNCTION: Plays a role in the normal development of the peripheral and central nervous system . Required for the correct localization of aurora kinase AURKA and the microtubule minus end-binding protein NUMA1 as well as a subset of AURKA targets which ensures proper spindle formation and timely chromosome alignment . .

AccessionsF8VZ44
ENST00000548931.6
ENST00000547757.2
ENST00000708962.1 [Q9NRG9-2]
Q9NRG9
ENST00000394384.7 [Q9NRG9-2]
D9DBT2
ENST00000708963.1 [Q9NRG9-1]
D9DBT0
H3BU82
D9DBT1
F8VUB6
D9DBS9
ENST00000550286.5
ENST00000209873.9 [Q9NRG9-1]
D9DBT3