Nkx-2.5 complex

I. Literature review

[source]
NameNkx-2.5 complex
IDGO_1990664
collection_id

Cellular component

Description

A transcription factor complex formed by two or more subunits of Nkx-2.5. Nkx-2.5 is an evolutionary conserved transcription factor important for the specification and differentiation of cardiomyocytes during heart development. It is also required for spleen development. It binds DNA either as a monomer, or a homodimer, or a heterodimer complex to activate or inhibit expression of genes.

Related synonym

NKX.2-5 homodimer complex, NKX2.5 complex, NKX2E homodimer complex

Comment

An example of this is Nkx-2.5 in human (UniProt symbol P52952) in PMID:22849347 (inferred from direct assay).

External URL
Genes