Name | Nkx-2.5 complex |
ID | GO_1990664 |
collection_id | Cellular component |
Description | A transcription factor complex formed by two or more subunits of Nkx-2.5. Nkx-2.5 is an evolutionary conserved transcription factor important for the specification and differentiation of cardiomyocytes during heart development. It is also required for spleen development. It binds DNA either as a monomer, or a homodimer, or a heterodimer complex to activate or inhibit expression of genes. |
Related synonym | NKX.2-5 homodimer complex, NKX2.5 complex, NKX2E homodimer complex |
Comment | An example of this is Nkx-2.5 in human (UniProt symbol P52952) in PMID:22849347 (inferred from direct assay). |
External URL | |
Genes |