| Name | CLOCK-BMAL transcription complex |
| ID | GO_1990513 |
| collection_id | Cellular component |
| Exact synonym | CLOCK/BMAL complex |
| Description | Transcription factor complex which interacts with E-box regulatory elements in target genes, including Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2), to activate their transcription during the daytime. The CRY-PER complexes inhibit CLOCK-BMAL1-driven transcription in a negative feedback loop to generate circadian rhythms. |
| Comment | An example of this is CLOCK in human (O15516) in PMID:23229515 (inferred from physical interaction). |
| External URL | |
| Genes |