target-directed miRNA degradation

I. Literature review

[source]
Nametarget-directed miRNA degradation
IDGO_0140958
collection_id

Biological process

Exact synonym

TDMD, target-directed microRNA degradation

Description

The process in which a miRNA is targeted for degradation by a non-coding RNA or mRNA. The binding of an RNA to a target miRNA within a RISC complex results in either ubiquitin-mediated degradation of AGO protein or the displacement of the 3' end of the miRNA, exposing it to nucleases.

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Genes