histone H3K27 dimethyltransferase activity

I. Literature review

[source]
Namehistone H3K27 dimethyltransferase activity
IDGO_0140952
collection_id

Molecular function

Exact synonym

histone H3-K27 dimethylase activity, histone H3K27 dimethylase activity, histone H3K27 mono/dimethylase activity, histone lysine N-dimethyltransferase activity (H3-K27 specific)

Description

Catalysis of the reaction: L-lysyl27-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl27-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me2.

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Genes