5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity

I. Literature review

[source]
Name5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity
IDGO_0140932
collection_id

Molecular function

Exact synonym

m(7)GpppN m(7)GMP phosphohydrolase activity, m(7)GpppX diphosphatase activity, m(7)GpppX pyrophosphatase activity

Description

Catalysis of the reaction: a 5'-end (N2,N2,N7-trimethyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = a 5'-end diphospho-ribonucleoside in mRNA + 2 H+ + N7-methyl-GMP. Can also use (N7-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA as a substrate.

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Genes