RNA NAD+-cap (NAD+-forming) hydrolase activity

I. Literature review

[source]
NameRNA NAD+-cap (NAD+-forming) hydrolase activity
IDGO_0110152
collection_id

Molecular function

Exact synonym

RNA NAD-cap (NAD-forming) hydrolase activity

Description

Catalysis of the reaction: a 5'-end NAD+-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + H+ + NAD+.

Comment

This reaction specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.

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Genes