medium-chain fatty acyl-CoA dehydrogenase activity

I. Literature review

[source]
Namemedium-chain fatty acyl-CoA dehydrogenase activity
IDGO_0070991
collection_id

Molecular function

Exact synonym

MCAD activity

Description

Catalysis of the reaction: a medium-chain 2,3-saturated fatty acyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = a medium-chain trans-(2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.

Comment

While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).

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