isotype switching to IgG isotypes

I. Literature review

[source]
Nameisotype switching to IgG isotypes
IDGO_0048291
collection_id

Biological process

Exact synonym

class switching to IgG isotypes, isotype switch recombination to IgG isotypes

Description

The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus.

External URL
Genes