XTP diphosphatase activity

I. Literature review

[source]
NameXTP diphosphatase activity
IDGO_0036222
collection_id

Molecular function

Alternative ID

GO:0103024

Exact synonym

XTP pyrophosphohydrolase activity, XTPase activity

Description

Catalysis of the reaction: XTP + H2O = XMP + H+ + diphosphate.

Related synonym

XTP/dITP diphosphatase, hypoxanthine/xanthine dNTP pyrophosphatase

Comment

While XTP is not produced by cells, deamination of purine bases can result in accumulation of such nucleotides as ITP, dITP, XTP, and dXTP. XTPase contributes to the removal of these abnormal bases from the cellular pool of nucleotide triphosphates.

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