Molecular function

Catalysis of the reaction: a long-chain (3S)-3-hydroxy fatty acyl-CoA + NAD+ = a long-chain 3-oxo-fatty acyl-CoA + H+ + NADH. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.

LCHAD, beta-hydroxyacyl-CoA dehydrogenase activity, long-chain 3-hydroxyacyl coenzyme A dehydrogenase activity, long-chain-(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase activity

While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).