Molecular function

linoleoyl CoA desaturase activity, linoleoyl-coenzyme A desaturase activity

Catalysis of the reaction: (9Z,12Z)-octadecadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = (6Z,9Z,12Z)-octadecatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O. Can also use a substrate with 3 double bonds (a (9Z,12Z,15Z)-octadecatrienoyl-CoA and add a fourth double bond (a (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA).

delta6-acyl CoA desaturase activity, delta6-desaturase activity, delta6-fatty acyl-CoA desaturase activity, fatty acid delta6-desaturase activity, linoleate desaturase activity, linoleic acid desaturase activity, linoleic desaturase activity, long-chain fatty acid delta6-desaturase activity