folate:monoatomic anion antiporter activity

I. Literature review

[source]
Namefolate:monoatomic anion antiporter activity
IDGO_0008518
collection_id

Molecular function

Description

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Folate derivative (out) + anion (in) = folate derivative (in) + anion (out). The Reduced Folate Carrier (RCF(SLC19A1) acts by an antiport mechanism. RCF carries several folate derivatives: MTX, PMX, ratitrexed, pralatrexate, 5-methyl THF, and 5-formyl THF.

Related synonym

reduced folate carrier activity, reduced folate transmembrane transporter activity, reduced folate transporter

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Genes