Molecular function

GO:0033817

3-oxoacyl-ACP synthase activity, 3-oxoacyl-[acyl-carrier protein] synthase activity, ketoacyl-ACP synthase activity

Catalysis of the reaction: acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein].

3-ketoacyl-acyl carrier protein synthase activity, 3-oxoacyl-acyl-carrier-protein synthase activity, acyl-acyl-carrier-protein:malonyl-acyl-carrier-protein C-acyltransferase (decarboxylating), acyl-malonyl acyl carrier protein-condensing enzyme activity, acyl-malonyl(acyl-carrier-protein)-condensing enzyme activity, beta-ketoacyl acyl carrier protein synthase activity, beta-ketoacyl synthetase activity, beta-ketoacyl-ACP synthetase activity, beta-ketoacyl-[acyl carrier protein] synthase activity, beta-ketoacyl-acyl carrier protein synthase activity, beta-ketoacyl-acyl carrier protein synthetase activity, beta-ketoacylsynthase activity

Note that this activity is responsible for the chain-elongation step of dissociated (type II) fatty-acid biosynthesis, i.e. the addition of two C atoms to the fatty-acid chain. Can use fatty acyl thioesters of ACP (C2 to C16) as substrates, as well as fatty acyl thioesters of Co-A (C4 to C16).