Molecular function

Catalysis of the reaction: ATP + biotin + apo-(acetyl-CoA:carbon-dioxide ligase (ADP forming)) = AMP + diphosphate + (acetyl-CoA:carbon-dioxide ligase (ADP forming)).

HCS, acetyl CoA holocarboxylase synthetase activity, acetyl coenzyme A holocarboxylase synthetase activity, acetyl-CoA carboxylase biotin holoenzyme synthetase activity, biotin holoenzyme synthetase activity, biotin--[acetyl-CoA carboxylase] synthetase activity, biotin--protein ligase activity, biotin-acetyl coenzyme A carboxylase synthetase activity, biotin-acetyl-CoA-carboxylase ligase activity, biotin:apo-acetyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming), biotin:apocarboxylase ligase activity