Biological process

TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent exogenous peptide antigen processing and presentation via MHC class I, exogenous peptide antigen processing and presentation via MHC class I, TAP-dependent

The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules.