natural killer cell mediated cytotoxicity directed against tumor cell target

I. Literature review

[source]
Namenatural killer cell mediated cytotoxicity directed against tumor cell target
IDGO_0002420
collection_id

Biological process

Exact synonym

NK cell mediated cytotoxicity directed against tumor cell target

Description

The directed killing of a tumor cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.

Comment

Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in induction of apoptosis in the target cell.

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Genes