Molecular function

Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. This reaction is the second step of the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane.

6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol acetylhydrolase activity, GlcNAc-PI de-N-acetylase activity, GlcNAc-PI deacetylase activity, N-acetyl-D-glucosaminylphosphatidylinositol acetylhydrolase activity, N-acetylglucosaminylphosphatidylinositol de-N-acetylase activity, acetylglucosaminylphosphatidylinositol deacetylase activity

Note that this function was formerly EC:3.1.1.69.