Name | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
ID | GO_0000224 |
collection_id | Molecular function |
Exact synonym | PNGase |
Description | Catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue. |
Related synonym | N-glycanase activity, N-linked-glycopeptide-(N-acetyl-beta-D-glucosaminyl)-L-asparagine amidohydrolase activity, N-oligosaccharide glycopeptidase activity, PNGase A, PNGase F, peptide:N-glycanase |
External URL | |
Genes |