osteoclast report

I. Related cell sub types

II. Gene markers

Gene
Number of
supported studies
Average coverage
Other major groups
(express this gene)
Other cell types
(express this gene)

III. Associated gene sets

GO_0097186Biological processamelogenesis
GO_0043377Biological processnegative regulation of CD8-positive, alpha-beta T cell differentiation
GO_1901029Biological processnegative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
GO_0070175Biological processpositive regulation of enamel mineralization

IV. Literature review

[source]
Cell type nameosteoclast
Synonyms
DescriptionA specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive.
ParentCL_0000518