ID | Name | Number of studies | |
---|---|---|---|
CL_0000864 | tissue-resident macrophage | 7 | |
CL_0000091 | Kupffer cell | 3 |
Gene | Number of supported studies | Average coverage | Other major groups (express this gene) | Other cell types (express this gene) |
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No associated gene sets found.
Cell type name | Kupffer cell |
Synonyms | hepatic macrophage littoral cell of hepatic sinusoid liver macrophage macrophagocytus stellatus stellate cell of von Kupffer von Kupffer cell |
Description | A tissue-resident macrophage of the reticuloendothelial system found on the luminal surface of the hepatic sinusoids involved in erythrocyte clearance. Markers include F4/80+, CD11b-low, CD68-positive, sialoadhesin-positive, CD163/SRCR-positive. Irregular, with long processes including lamellipodia extending into the sinusoid lumen, have flattened nucleus with cytoplasm containing characteristic invaginations of the plasma membrane (vermiform bodies); lie within the sinusoid lumen attached to the endothelial surface; derived from the bone marrow, form a major part of the body's mononuclear phagocyte system. |
Parent | CL_0000864 |