Kupffer cell report

I. Related cell sub types

II. Gene markers

Gene
Number of
supported studies
Average coverage
Other major groups
(express this gene)
Other cell types
(express this gene)

III. Associated gene sets

No associated gene sets found.

IV. Literature review

[source]
Cell type nameKupffer cell
Synonymshepatic macrophage
littoral cell of hepatic sinusoid
liver macrophage
macrophagocytus stellatus
stellate cell of von Kupffer
von Kupffer cell
DescriptionA tissue-resident macrophage of the reticuloendothelial system found on the luminal surface of the hepatic sinusoids involved in erythrocyte clearance. Markers include F4/80+, CD11b-low, CD68-positive, sialoadhesin-positive, CD163/SRCR-positive. Irregular, with long processes including lamellipodia extending into the sinusoid lumen, have flattened nucleus with cytoplasm containing characteristic invaginations of the plasma membrane (vermiform bodies); lie within the sinusoid lumen attached to the endothelial surface; derived from the bone marrow, form a major part of the body's mononuclear phagocyte system.
ParentCL_0000864