I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 20% ± 5% | |
| GABAergic neuron | 3 studies | 21% ± 6% | |
| glutamatergic neuron | 3 studies | 29% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 20% ± 5% | |
| GABAergic neuron | 3 studies | 21% ± 6% | |
| glutamatergic neuron | 3 studies | 29% ± 6% |
Insufficient scRNA-seq data for expression of ZNF518B at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 1806.06 | 245 / 245 | 99% | 12.73 | 499 / 502 |
| thymus | 100% | 1340.19 | 653 / 653 | 96% | 9.31 | 579 / 605 |
| uterus | 100% | 1382.28 | 170 / 170 | 94% | 8.57 | 433 / 459 |
| breast | 100% | 1090.53 | 459 / 459 | 92% | 9.36 | 1033 / 1118 |
| adrenal gland | 100% | 1185.06 | 258 / 258 | 91% | 6.06 | 210 / 230 |
| skin | 100% | 1211.05 | 1802 / 1809 | 90% | 10.80 | 426 / 472 |
| lung | 100% | 967.81 | 576 / 578 | 90% | 8.09 | 1040 / 1155 |
| ovary | 100% | 1716.59 | 180 / 180 | 87% | 6.04 | 373 / 430 |
| bladder | 100% | 1327.29 | 21 / 21 | 78% | 5.87 | 395 / 504 |
| brain | 100% | 1038.74 | 2638 / 2642 | 76% | 5.70 | 536 / 705 |
| kidney | 100% | 739.51 | 89 / 89 | 71% | 3.48 | 638 / 901 |
| esophagus | 100% | 1288.45 | 1444 / 1445 | 70% | 7.31 | 129 / 183 |
| stomach | 100% | 882.95 | 359 / 359 | 59% | 3.54 | 168 / 286 |
| intestine | 100% | 1484.53 | 966 / 966 | 52% | 2.88 | 274 / 527 |
| pancreas | 66% | 210.12 | 215 / 328 | 69% | 3.59 | 122 / 178 |
| adipose | 100% | 1080.59 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1216.29 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 5.58 | 1 / 1 |
| muscle | 100% | 970.49 | 802 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 791.37 | 1327 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 1015.31 | 853 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 9.41 | 44 / 45 |
| eye | 0% | 0 | 0 / 0 | 93% | 6.51 | 74 / 80 |
| liver | 62% | 207.39 | 141 / 226 | 21% | 0.83 | 84 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 72% | 4.09 | 21 / 29 |
| peripheral blood | 72% | 605.09 | 671 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006325 | Biological process | chromatin organization |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0005634 | Cellular component | nucleus |
| GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | ZNF518B |
| Protein name | Zinc finger protein 518B |
| Synonyms | KIAA1729 |
| Description | FUNCTION: Through its association with the EHMT1-EHMT2/G9A and PRC2/EED-EZH2 histone methyltransferase complexes may function in gene silencing, regulating repressive post-translational methylation of histone tails at promoters of target genes. . |
| Accessions | D6RDM9 Q9C0D4 ENST00000507515.1 ENST00000326756.4 |
