I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 3 studies | 20% ± 1% | |
| glutamatergic neuron | 3 studies | 21% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 3 studies | 20% ± 1% | |
| glutamatergic neuron | 3 studies | 21% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 19% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 502.94 | 576 / 578 | 100% | 7.26 | 1151 / 1155 |
| brain | 99% | 335.84 | 2622 / 2642 | 100% | 7.30 | 703 / 705 |
| thymus | 100% | 517.14 | 653 / 653 | 99% | 6.96 | 597 / 605 |
| kidney | 100% | 386.30 | 89 / 89 | 99% | 6.80 | 889 / 901 |
| prostate | 100% | 540.36 | 245 / 245 | 99% | 6.52 | 495 / 502 |
| esophagus | 100% | 475.22 | 1445 / 1445 | 98% | 5.23 | 180 / 183 |
| breast | 100% | 661.17 | 459 / 459 | 98% | 7.50 | 1099 / 1118 |
| bladder | 100% | 625.43 | 21 / 21 | 98% | 6.61 | 494 / 504 |
| pancreas | 100% | 296.53 | 327 / 328 | 98% | 5.84 | 175 / 178 |
| stomach | 100% | 425.20 | 359 / 359 | 98% | 6.10 | 280 / 286 |
| uterus | 100% | 722.71 | 170 / 170 | 97% | 6.64 | 447 / 459 |
| intestine | 100% | 572.32 | 966 / 966 | 97% | 6.49 | 513 / 527 |
| adrenal gland | 99% | 532.13 | 256 / 258 | 97% | 5.40 | 224 / 230 |
| skin | 100% | 671.67 | 1809 / 1809 | 95% | 7.34 | 449 / 472 |
| ovary | 100% | 644.04 | 180 / 180 | 95% | 5.06 | 408 / 430 |
| liver | 100% | 265.54 | 225 / 226 | 86% | 3.91 | 350 / 406 |
| adipose | 100% | 625.34 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 5.72 | 29 / 29 |
| spleen | 100% | 606.34 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 6.90 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 2.53 | 1 / 1 |
| blood vessel | 100% | 517.51 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 100% | 554.33 | 801 / 803 | 0% | 0 | 0 / 0 |
| heart | 97% | 395.40 | 836 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 76% | 3.69 | 61 / 80 |
| peripheral blood | 52% | 291.86 | 481 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0045727 | Biological process | positive regulation of translation |
| GO_0031167 | Biological process | rRNA methylation |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005737 | Cellular component | cytoplasm |
| GO_1904047 | Molecular function | S-adenosyl-L-methionine binding |
| GO_0008988 | Molecular function | rRNA (adenine-N6-)-methyltransferase activity |
| GO_0008270 | Molecular function | zinc ion binding |
| GO_0003676 | Molecular function | nucleic acid binding |
| Gene name | ZCCHC4 |
| Protein name | rRNA N6-adenosine-methyltransferase ZCCHC4 (EC 2.1.1.-) (Zinc finger CCHC domain-containing protein 4) Zinc finger CCHC-type containing 4 |
| Synonyms | |
| Description | FUNCTION: rRNA N6-methyltransferase that specifically methylates the adenine in position 4220 of 28S rRNA . N6-methylation of adenine(4220) in 28S rRNA is required for translation . . |
| Accessions | ENST00000505412.1 Q9H5U6 ENST00000302874.9 [Q9H5U6-1] H0Y8V8 ENST00000507760.5 [Q9H5U6-2] |
