ZAR1L report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ZAR1L at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ZAR1L at tissue level.

III. Associated gene sets

GO_0001556Biological processoocyte maturation
GO_0006412Biological processtranslation
GO_0017148Biological processnegative regulation of translation
GO_0043232Cellular componentintracellular non-membrane-bounded organelle
GO_0005737Cellular componentcytoplasm
GO_0036464Cellular componentcytoplasmic ribonucleoprotein granule
GO_0003730Molecular functionmRNA 3'-UTR binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameZAR1L
Protein nameProtein ZAR1-like (Zygote arrest protein 1-like)
Synonyms
DescriptionFUNCTION: mRNA-binding protein required for maternal mRNA storage, translation and degradation during oocyte maturation (By similarity). Probably promotes formation of some phase-separated membraneless compartment that stores maternal mRNAs in oocytes: acts by undergoing liquid-liquid phase separation upon binding to maternal mRNAs (By similarity). Binds to the 3'-UTR of maternal mRNAs, inhibiting their translation (By similarity). .

AccessionsA6NP61
ENST00000533490.7
ENST00000345108.6