Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| enterocyte | 6 studies | 32% ± 6% |
Insufficient scRNA-seq data for expression of XPNPEP2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 95% | 2994.49 | 921 / 966 | 71% | 12.38 | 373 / 527 |
| stomach | 65% | 486.70 | 233 / 359 | 79% | 16.66 | 227 / 286 |
| liver | 75% | 1065.62 | 169 / 226 | 66% | 45.92 | 268 / 406 |
| kidney | 96% | 6032.46 | 85 / 89 | 41% | 4.64 | 370 / 901 |
| skin | 93% | 811.65 | 1677 / 1809 | 38% | 1.19 | 177 / 472 |
| bladder | 95% | 1124.95 | 20 / 21 | 32% | 3.77 | 161 / 504 |
| esophagus | 87% | 608.49 | 1253 / 1445 | 38% | 5.11 | 70 / 183 |
| breast | 87% | 505.02 | 398 / 459 | 33% | 0.93 | 367 / 1118 |
| lung | 74% | 353.32 | 427 / 578 | 34% | 2.32 | 389 / 1155 |
| adipose | 97% | 1107.34 | 1166 / 1204 | 0% | 0 | 0 / 0 |
| uterus | 71% | 491.92 | 120 / 170 | 18% | 1.74 | 83 / 459 |
| blood vessel | 81% | 442.01 | 1088 / 1335 | 0% | 0 | 0 / 0 |
| thymus | 62% | 237.40 | 403 / 653 | 19% | 0.84 | 113 / 605 |
| heart | 63% | 356.34 | 540 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 62% | 1.74 | 18 / 29 |
| ovary | 48% | 266.57 | 86 / 180 | 8% | 0.69 | 35 / 430 |
| adrenal gland | 49% | 127.76 | 126 / 258 | 3% | 1.64 | 7 / 230 |
| prostate | 39% | 288.41 | 95 / 245 | 5% | 0.07 | 24 / 502 |
| pancreas | 6% | 9.73 | 21 / 328 | 37% | 3.33 | 66 / 178 |
| brain | 0% | 0.06 | 1 / 2642 | 28% | 0.80 | 199 / 705 |
| peripheral blood | 16% | 30.69 | 153 / 929 | 0% | 0 | 0 / 0 |
| muscle | 12% | 24.67 | 96 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 9% | 0.13 | 4 / 45 |
| spleen | 2% | 3.27 | 4 / 241 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006508 | Biological process | proteolysis |
| GO_0098552 | Cellular component | side of membrane |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0070006 | Molecular function | metalloaminopeptidase activity |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0004177 | Molecular function | aminopeptidase activity |
| Gene name | XPNPEP2 |
| Protein name | X-prolyl aminopeptidase (Aminopeptidase P) 2, membrane-bound Xaa-Pro aminopeptidase 2 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Membrane-bound aminopeptidase P) (Membrane-bound APP) (Membrane-bound AmP) (mAmP) (X-Pro aminopeptidase 2) |
| Synonyms | |
| Description | FUNCTION: Membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. May play a role in the metabolism of the vasodilator bradykinin. . |
| Accessions | ENST00000371106.4 O43895 B7ZLM6 |