XPNPEP2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of XPNPEP2 at tissue level.

III. Associated gene sets

GO_0006508Biological processproteolysis
GO_0098552Cellular componentside of membrane
GO_0070062Cellular componentextracellular exosome
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0070006Molecular functionmetalloaminopeptidase activity
GO_0046872Molecular functionmetal ion binding
GO_0004177Molecular functionaminopeptidase activity

IV. Literature review

[source]
Gene nameXPNPEP2
Protein nameX-prolyl aminopeptidase (Aminopeptidase P) 2, membrane-bound
Xaa-Pro aminopeptidase 2 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Membrane-bound aminopeptidase P) (Membrane-bound APP) (Membrane-bound AmP) (mAmP) (X-Pro aminopeptidase 2)
Synonyms
DescriptionFUNCTION: Membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. May play a role in the metabolism of the vasodilator bradykinin. .

AccessionsENST00000371106.4
O43895
B7ZLM6