WARS2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0001570Biological processvasculogenesis
GO_0006418Biological processtRNA aminoacylation for protein translation
GO_0045766Biological processpositive regulation of angiogenesis
GO_0070183Biological processmitochondrial tryptophanyl-tRNA aminoacylation
GO_0005654Cellular componentnucleoplasm
GO_0005886Cellular componentplasma membrane
GO_0005759Cellular componentmitochondrial matrix
GO_0005739Cellular componentmitochondrion
GO_0004830Molecular functiontryptophan-tRNA ligase activity
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameWARS2
Protein nameTryptophan--tRNA ligase, mitochondrial (EC 6.1.1.2) ((Mt)TrpRS) (Tryptophanyl-tRNA synthetase) (TrpRS)
Synonyms
DescriptionFUNCTION: Catalyzes the attachment of tryptophan to tRNA(Trp) in a two-step reaction: tryptophan is first activated by ATP to form Trp-AMP and then transferred to the acceptor end of tRNA(Trp). .

AccessionsQ9UGM6
ENST00000235521.5 [Q9UGM6-1]
ENST00000369426.9 [Q9UGM6-2]