VSTM5 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of VSTM5 at tissue level.

III. Associated gene sets

GO_0046847Biological processfilopodium assembly
GO_0051260Biological processprotein homooligomerization
GO_1904891Biological processpositive regulation of excitatory synapse assembly
GO_0021517Biological processventral spinal cord development
GO_0030424Cellular componentaxon
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0030425Cellular componentdendrite

IV. Literature review

[source]
Gene nameVSTM5
Protein nameV-set and transmembrane domain-containing protein 5
V-set and transmembrane domain containing 5
SynonymsC11orf90
DescriptionFUNCTION: Cell adhesion-like membrane protein of the central nervous system (CNS) which modulates both the position and complexity of central neurons by altering their membrane morphology and dynamics. Involved in the formation of neuronal dendrites and protrusions including dendritic filopodia. In synaptogenesis, regulates synapse formation by altering dendritic spine morphology and actin distribution. Promotes formation of unstable neuronal spines such as thin and branched types. Regulates neuronal morphogenesis and migration during cortical development in the brain. .

AccessionsENST00000409977.2
A8MXK1
H0Y3Q1
ENST00000398221.3