UQCC3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0034551Biological processmitochondrial respiratory chain complex III assembly
GO_0006122Biological processmitochondrial electron transport, ubiquinol to cytochrome c
GO_0042407Biological processcristae formation
GO_0006754Biological processATP biosynthetic process
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005750Cellular componentmitochondrial respiratory chain complex III
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005739Cellular componentmitochondrion
GO_0070300Molecular functionphosphatidic acid binding
GO_1901612Molecular functioncardiolipin binding

IV. Literature review

[source]
Gene nameUQCC3
Protein nameUbiquinol-cytochrome-c reductase complex assembly factor 3 (Assembly factor CBP4 homolog)
SynonymsC11orf83
UNQ655/PRO1286
DescriptionFUNCTION: Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology. .

AccessionsENST00000377953.4
Q6UW78
ENST00000531323.1