UMPS report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006207Biological process'de novo' pyrimidine nucleobase biosynthetic process
GO_0007595Biological processlactation
GO_0071466Biological processcellular response to xenobiotic stimulus
GO_0006225Biological processUDP biosynthetic process
GO_0044205Biological process'de novo' UMP biosynthetic process
GO_0019856Biological processpyrimidine nucleobase biosynthetic process
GO_0007565Biological processfemale pregnancy
GO_0006222Biological processUMP biosynthetic process
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0004590Molecular functionorotidine-5'-phosphate decarboxylase activity
GO_0004588Molecular functionorotate phosphoribosyltransferase activity

IV. Literature review

[source]
Gene nameUMPS
Protein nameUridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10); Orotidine 5'-phosphate decarboxylase (ODC) (OMPD) (EC 4.1.1.23) (OMPdecase)]
Uridine monophosphate synthetase isoform E
Uridine monophosphate synthetase
Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)
Uridine 5'-monophosphate synthase (EC 2.4.2.10) (EC 4.1.1.23)
SynonymsOK/SW-cl.21
hCG_1780791
DescriptionFUNCTION: Bifunctional enzyme catalyzing the last two steps of de novo pyrimidine biosynthesis, orotate phosphoribosyltransferase (OPRT), which converts orotate to orotidine-5'-monophosphate (OMP), and orotidine-5'-monophosphate decarboxylase (ODC), the terminal enzymatic reaction that decarboxylates OMP to uridine monophosphate (UMP). .

AccessionsENST00000232607.7 [P11172-1]
ENST00000462091.5
B5LY70
B5LY71
ENST00000479719.5
A8K5J1
E9PFD2
B5LY69
F2Z3P2
B5LY67
ENST00000628619.1
F8WDG4
P11172
B5LY64
ENST00000460034.5
ENST00000467167.5
ENST00000474588.5
ENST00000497791.5
F2Z303