Insufficient scRNA-seq data for expression of UBR7 at single-cell level.
Insufficient scRNA-seq data for expression of UBR7 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 2478.35 | 2642 / 2642 | 100% | 63.24 | 705 / 705 |
breast | 100% | 2173.89 | 459 / 459 | 100% | 63.49 | 1118 / 1118 |
esophagus | 100% | 2076.33 | 1445 / 1445 | 100% | 36.48 | 183 / 183 |
lung | 100% | 1845.67 | 578 / 578 | 100% | 35.65 | 1155 / 1155 |
ovary | 100% | 2061.76 | 180 / 180 | 100% | 30.13 | 430 / 430 |
prostate | 100% | 1863.44 | 245 / 245 | 100% | 39.65 | 502 / 502 |
stomach | 100% | 1752.31 | 359 / 359 | 100% | 29.87 | 286 / 286 |
uterus | 100% | 2037.20 | 170 / 170 | 100% | 51.02 | 459 / 459 |
kidney | 100% | 1568.92 | 89 / 89 | 100% | 41.47 | 900 / 901 |
thymus | 100% | 1964.27 | 653 / 653 | 100% | 40.37 | 603 / 605 |
intestine | 100% | 2129.16 | 966 / 966 | 100% | 31.13 | 525 / 527 |
bladder | 100% | 2006.10 | 21 / 21 | 100% | 33.93 | 502 / 504 |
skin | 100% | 2296.37 | 1809 / 1809 | 99% | 43.52 | 469 / 472 |
pancreas | 100% | 1564.68 | 327 / 328 | 99% | 30.37 | 176 / 178 |
adrenal gland | 100% | 1763.53 | 258 / 258 | 98% | 34.07 | 225 / 230 |
liver | 100% | 923.33 | 226 / 226 | 96% | 18.48 | 391 / 406 |
adipose | 100% | 2034.84 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2207.35 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 46.38 | 29 / 29 |
spleen | 100% | 1864.38 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 49.15 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 15.91 | 1 / 1 |
muscle | 100% | 1745.18 | 802 / 803 | 0% | 0 | 0 / 0 |
heart | 98% | 1761.48 | 844 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 96% | 25.72 | 77 / 80 |
peripheral blood | 85% | 1932.50 | 793 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0016567 | Biological process | protein ubiquitination |
GO_0008150 | Biological process | biological_process |
GO_0061630 | Molecular function | ubiquitin protein ligase activity |
GO_0008270 | Molecular function | zinc ion binding |
GO_0003674 | Molecular function | molecular_function |
Gene name | UBR7 |
Protein name | Putative E3 ubiquitin-protein ligase UBR7 Putative E3 ubiquitin-protein ligase UBR7 (EC 2.3.2.27) (N-recognin-7) (RING-type E3 ubiquitin transferase UBR7) Putative E3 ubiquitin-protein ligase UBR7 (Ubiquitin protein ligase E3 component n-recognin 7) Ubiquitin protein ligase E3 component n-recognin 7 UBR7 protein Alternative protein UBR7 |
Synonyms | C14orf130 |
Description | FUNCTION: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. . |
Accessions | ENST00000013070.11 E9PCJ7 ENST00000628088.2 G3V2G3 Q8N806 H0YJM2 ENST00000625851.2 H0YJY4 ENST00000553857.5 ENST00000553674.1 ENST00000625902.2 ENST00000611035.3 ENST00000555329.1 ENST00000554232.5 ENST00000619583.3 G3V336 ENST00000556871.5 ENST00000627299.2 ENST00000555113.5 ENST00000630635.2 L8E9R4 H0YJA0 Q05DA8 G3V253 |