TUBA3C report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TUBA3C at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TUBA3C at tissue level.

III. Associated gene sets

GO_0000278Biological processmitotic cell cycle
GO_0000226Biological processmicrotubule cytoskeleton organization
GO_0015630Cellular componentmicrotubule cytoskeleton
GO_0005874Cellular componentmicrotubule
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0005525Molecular functionGTP binding
GO_0005200Molecular functionstructural constituent of cytoskeleton
GO_0016787Molecular functionhydrolase activity
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameTUBA3C
Protein nameTubulin alpha-3C chain (EC 3.6.5.-) (Alpha-tubulin 2) (Alpha-tubulin 3C) (Tubulin alpha-2 chain) [Cleaved into: Detyrosinated tubulin alpha-3C chain]
SynonymsTUBA2
DescriptionFUNCTION: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

AccessionsENST00000400113.8 [P0DPH7-1]
P0DPH7