TSPAN17 | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell	4 studies	21% ± 6%	Explore
erythrocyte	3 studies	24% ± 5%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of TSPAN17 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	1473.04	180 / 180	100%	32.31	430 / 430
pancreas	100%	1838.40	328 / 328	100%	37.43	178 / 178
uterus	100%	1755.01	170 / 170	100%	37.81	459 / 459
lung	100%	2299.16	578 / 578	100%	36.16	1154 / 1155
stomach	100%	1960.11	358 / 359	100%	26.24	286 / 286
kidney	100%	2748.12	89 / 89	100%	29.14	898 / 901
esophagus	100%	1946.27	1445 / 1445	99%	24.20	182 / 183
bladder	100%	2001.71	21 / 21	99%	35.64	501 / 504
prostate	100%	2477.41	245 / 245	99%	28.12	499 / 502
skin	100%	2318.59	1809 / 1809	99%	36.70	469 / 472
thymus	100%	2109.60	653 / 653	99%	23.17	601 / 605
breast	100%	1690.39	459 / 459	99%	34.87	1110 / 1118
intestine	100%	1956.23	966 / 966	99%	33.00	523 / 527
brain	99%	1854.43	2621 / 2642	100%	25.61	705 / 705
liver	100%	1313.06	226 / 226	99%	23.51	401 / 406
adrenal gland	100%	4723.62	258 / 258	97%	41.54	223 / 230
adipose	100%	1633.79	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	34.86	29 / 29
muscle	100%	2411.59	803 / 803	0%	0	0 / 0
spleen	100%	2824.42	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	50.31	45 / 45
ureter	0%	0	0 / 0	100%	9.07	1 / 1
blood vessel	100%	1228.28	1331 / 1335	0%	0	0 / 0
heart	99%	1706.94	856 / 861	0%	0	0 / 0
peripheral blood	99%	1254.88	919 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	99%	25.25	79 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

Gene name	TSPAN17
Protein name	Tetraspanin 17 Tetraspanin-17 (Tspan-17) (F-box only protein 23) (Tetraspan protein SB134) (Transmembrane 4 superfamily member 17) Tetraspanin
Synonyms	TM4SF17 FBXO23
Description	FUNCTION: Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates . Seems to regulate VE-cadherin expression in endothelial cells probably through interaction with ADAM10, promoting leukocyte transmigration . .
Accessions	D6RI03 ENST00000310032.12 J3KNG2 D6RBW9 ENST00000507471.1 ENST00000504168.5 Q96FV3 ENST00000503045.5 D6RDX8 ENST00000508164.6 [Q96FV3-4] ENST00000515708.5 [Q96FV3-3] ENST00000503030.1 ENST00000298564.14 [Q96FV3-2] H0Y9A5

GO_0072594	Biological process	establishment of protein localization to organelle
GO_0051043	Biological process	regulation of membrane protein ectodomain proteolysis
GO_0005886	Cellular component	plasma membrane
GO_0019899	Molecular function	enzyme binding

TSPAN17 report