TRPM1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0051262Biological processprotein tetramerization
GO_0098703Biological processcalcium ion import across plasma membrane
GO_0007601Biological processvisual perception
GO_0007216Biological processG protein-coupled glutamate receptor signaling pathway
GO_0098655Biological processmonoatomic cation transmembrane transport
GO_0071482Biological processcellular response to light stimulus
GO_0030001Biological processmetal ion transport
GO_0070588Biological processcalcium ion transmembrane transport
GO_0030424Cellular componentaxon
GO_0005886Cellular componentplasma membrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005262Molecular functioncalcium channel activity

IV. Literature review

[source]
Gene nameTRPM1
Protein nameTransient receptor potential cation channel subfamily M member 1
Transient receptor potential cation channel subfamily M member 1 (Long transient receptor potential channel 1) (LTrpC1) (Melastatin-1)
SynonymsLTRPC1
MLSN
MLSN1
DescriptionFUNCTION: Forms nonselective divalent cation-conducting channels which mediate the influx of Na(+), Ca(2+), Mg(2+), Mn(2+), Ba(2+), and Ni(2+) into the cytoplasm, leading to membrane depolarization . Impermeable to zinc ions . In addition, forms heteromultimeric ion channels with TRPM3 which are permeable for calcium and zinc ions . Essential for the depolarizing photoresponse of retinal ON bipolar cells. It is part of the GRM6 signaling cascade. May play a role in metastasis suppression (By similarity). May act as a spontaneously active, calcium-permeable plasma membrane channel. .

AccessionsENST00000559179.2 [Q7Z4N2-7]
ENST00000397795.7 [Q7Z4N2-1]
ENST00000558768.5
C9EH86
A0A0A0MTR0
H0YM61
A0A0A0MTQ9
H0YKU7
ENST00000611448.4
ENST00000617515.4
ENST00000256552.11 [Q7Z4N2-6]
ENST00000621076.1
A0A0G2JPN6
ENST00000559177.6
ENST00000558445.6
A0A0G2JMJ5
A0A0G2JMR4
ENST00000560658.5 [Q7Z4N2-4]
ENST00000558445.6 [Q7Z4N2-5]
Q7Z4N2
ENST00000615583.4
A0A0G2JN34
ENST00000618210.4
ENST00000560801.5