Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 5 studies | 20% ± 4% | |
| GABAergic neuron | 4 studies | 33% ± 9% | |
| glutamatergic neuron | 4 studies | 44% ± 13% | |
| microglial cell | 3 studies | 21% ± 1% | |
| ciliated cell | 3 studies | 25% ± 6% | |
| epithelial cell | 3 studies | 26% ± 8% | |
| oligodendrocyte precursor cell | 3 studies | 26% ± 6% | |
| dendritic cell | 3 studies | 25% ± 6% | |
| interneuron | 3 studies | 34% ± 15% | |
| oligodendrocyte | 3 studies | 21% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 6 studies | 30% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| bladder | 100% | 1603.62 | 21 / 21 | 100% | 20.43 | 504 / 504 |
| breast | 100% | 1250.75 | 459 / 459 | 100% | 11.88 | 1118 / 1118 |
| esophagus | 100% | 1454.59 | 1445 / 1445 | 100% | 23.75 | 183 / 183 |
| ovary | 100% | 1461.84 | 180 / 180 | 100% | 13.88 | 430 / 430 |
| pancreas | 100% | 1210.76 | 328 / 328 | 100% | 10.06 | 178 / 178 |
| prostate | 100% | 2124.76 | 245 / 245 | 100% | 14.51 | 502 / 502 |
| thymus | 100% | 1914.31 | 653 / 653 | 100% | 12.05 | 605 / 605 |
| uterus | 100% | 1785.45 | 170 / 170 | 100% | 15.50 | 459 / 459 |
| lung | 100% | 1010.85 | 576 / 578 | 100% | 13.85 | 1155 / 1155 |
| intestine | 100% | 1301.63 | 966 / 966 | 100% | 10.59 | 525 / 527 |
| stomach | 100% | 986.28 | 359 / 359 | 99% | 8.69 | 283 / 286 |
| skin | 100% | 1924.91 | 1809 / 1809 | 99% | 10.18 | 466 / 472 |
| brain | 98% | 902.97 | 2592 / 2642 | 100% | 9.37 | 705 / 705 |
| liver | 100% | 666.78 | 226 / 226 | 96% | 5.18 | 391 / 406 |
| kidney | 100% | 1131.27 | 89 / 89 | 96% | 8.08 | 865 / 901 |
| adrenal gland | 100% | 944.43 | 258 / 258 | 96% | 5.61 | 220 / 230 |
| adipose | 100% | 977.56 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 9.39 | 29 / 29 |
| spleen | 100% | 1271.91 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 13.31 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 14.95 | 1 / 1 |
| blood vessel | 100% | 922.76 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 98% | 587.85 | 788 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 98% | 12.05 | 78 / 80 |
| heart | 97% | 973.42 | 831 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 53% | 591.54 | 488 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0070900 | Biological process | mitochondrial tRNA modification |
| GO_0006400 | Biological process | tRNA modification |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0052381 | Molecular function | tRNA dimethylallyltransferase activity |
| GO_0008270 | Molecular function | zinc ion binding |
| GO_0003676 | Molecular function | nucleic acid binding |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | TRIT1 |
| Protein name | tRNA isopentenyltransferase 1 tRNA isopentenylpyrophosphate transferase isoform 1 (EC 2.5.1.8) tRNA isopentenylpyrophosphate transferase isoform 7 (tRNA isopentenyltransferase 1) tRNA isopentenylpyrophosphate transferase isoform 3 tRNA isopentenylpyrophosphate transferase isoform 2 tRNA dimethylallyltransferase (EC 2.5.1.75) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPP transferase) (IPPT) (hGRO1) (tRNA isopentenyltransferase 1) (IPTase) TRIT1 protein tRNA isopentenylpyrophosphate transferase isoform 4 tRNA isopentenylpyrophosphate transferase isoform 5 cDNA FLJ60623, highly similar to tRNA isopentenyltransferase, mitochondrial (tRNA isopentenyltransferase 1) |
| Synonyms | IPT MOD5 |
| Description | FUNCTION: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethylallyl)adenosine (i6A37) . Mediates modification of a limited subset of tRNAs: tRNA(Ser)(AGA), tRNA(Ser)(CGA), tRNA(Ser)(UGA), as well as partial modification of the selenocysteine tRNA(Ser)(UCA) . TRIT1 is therefore required for selenoprotein expression . . |
| Accessions | Q3T7C7 ENST00000537440.5 [Q9H3H1-6] ENST00000316891.10 [Q9H3H1-1] ENST00000372818.5 [Q9H3H1-4] B4DK89 ENST00000469476.2 Q9H3H1 ENST00000648678.1 Q3T7C3 Q3T7B4 I6L9K0 ENST00000462797.5 ENST00000441669.6 [Q9H3H1-5] ENST00000492612.6 S4R3F4 A0A3B3ITK2 Q3T7C6 Q3T7B8 Q3T7C5 ENST00000495175.6 S4R2X1 ENST00000541099.5 S4R3U8 S4R3C5 ENST00000486825.6 ENST00000489945.5 S4R2Z0 |
