TPTE2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TPTE2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TPTE2 at tissue level.

III. Associated gene sets

GO_0034220Biological processmonoatomic ion transmembrane transport
GO_0016311Biological processdephosphorylation
GO_0006661Biological processphosphatidylinositol biosynthetic process
GO_0000139Cellular componentGolgi membrane
GO_0005829Cellular componentcytosol
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005216Molecular functionmonoatomic ion channel activity
GO_0016314Molecular functionphosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
GO_0051800Molecular functionphosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
GO_0004725Molecular functionprotein tyrosine phosphatase activity

IV. Literature review

[source]
Gene nameTPTE2
Protein nameTransmembrane phosphoinositide 3-phosphatase and tensin 2-like protein isoform 1
Voltage-gated hydrogen channel 1 (Hydrogen voltage-gated channel 1)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (Lipid phosphatase TPIP) (TPTE and PTEN homologous inositol lipid phosphatase)
Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
Transmembrane phosphoinositide 3-phosphatase and tensin 2-like protein isoform 2
SynonymsTPIP
hCG_2020790
DescriptionFUNCTION: Acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate. .; FUNCTION: [Isoform 4]: Shows no phosphoinositide phosphatase activity. .

AccessionsENST00000382978.5 [Q6XPS3-2]
ENST00000696859.1
ENST00000390680.2 [Q6XPS3-3]
A0A286KIS6
A0A8Q3SIW4
ENST00000696860.1
A0A8Q3SJ26
A0A1X9IX21
G3V171
ENST00000462409.5
Q6XPS3
A0A8Q3SJ67
ENST00000696857.1
ENST00000400103.7 [Q6XPS3-5]
ENST00000696861.1
ENST00000696858.2 [Q6XPS3-1]
A0A8Q3SJ09
ENST00000697147.1 [Q6XPS3-1]
ENST00000696988.1 [Q6XPS3-1]