TPO report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TPO at tissue level.

III. Associated gene sets

GO_0042446Biological processhormone biosynthetic process
GO_0042744Biological processhydrogen peroxide catabolic process
GO_0006590Biological processthyroid hormone generation
GO_0098869Biological processcellular oxidant detoxification
GO_0006979Biological processresponse to oxidative stress
GO_0035162Biological processembryonic hemopoiesis
GO_0005615Cellular componentextracellular space
GO_0009986Cellular componentcell surface
GO_0005886Cellular componentplasma membrane
GO_0004601Molecular functionperoxidase activity
GO_0005509Molecular functioncalcium ion binding
GO_0020037Molecular functionheme binding
GO_0004447Molecular functioniodide peroxidase activity

IV. Literature review

[source]
Gene nameTPO
Protein nameUncharacterized protein TPO
Thyroid peroxidase (EC 1.11.1.8)
Thyroid peroxidase
Thyroid peroxidase (TPO) (EC 1.11.1.8)
TPO protein
Synonyms
DescriptionFUNCTION: Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4). .

FUNCTION: Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4). .

FUNCTION: Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4). .

FUNCTION: Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4). .

FUNCTION: Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4). .

AccessionsENST00000345913.8 [P07202-1]
A0M8X1
Q57YV8
ENST00000382201.7 [P07202-2]
ENST00000382269.7
E9PFM6
Q16495
ENST00000346956.7 [P07202-4]
Q16496
Q53QT2
ENST00000469607.3
P07202
A0A3T0CIT9
ENST00000382198.5 [P07202-5]
ENST00000329066.9 [P07202-1]
ENST00000422464.5
Q502Y3
ENST00000446278.5
H0Y6H4
C9J511
H7C5B6
ENST00000539820.5
H7C1F5
Q6P534
ENST00000423320.5