Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| fibroblast | 38 studies | 54% ± 19% | |
| pericyte | 36 studies | 74% ± 26% | |
| smooth muscle cell | 34 studies | 78% ± 25% | |
| plasmacytoid dendritic cell | 23 studies | 62% ± 19% | |
| connective tissue cell | 16 studies | 63% ± 21% | |
| myofibroblast cell | 15 studies | 85% ± 13% | |
| endothelial cell | 13 studies | 33% ± 12% | |
| mesothelial cell | 11 studies | 64% ± 25% | |
| basal cell | 9 studies | 35% ± 18% | |
| cardiac muscle cell | 5 studies | 45% ± 11% | |
| myoepithelial cell | 5 studies | 80% ± 17% | |
| endothelial cell of artery | 4 studies | 30% ± 13% | |
| adventitial cell | 4 studies | 35% ± 10% | |
| epithelial cell | 4 studies | 34% ± 3% | |
| muscle cell | 4 studies | 70% ± 26% | |
| neural crest cell | 3 studies | 59% ± 10% | |
| B cell | 3 studies | 26% ± 6% | |
| endothelial cell of vascular tree | 3 studies | 48% ± 34% | |
| neuron | 3 studies | 37% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 89% | 101367.78 | 217 / 245 | 99% | 639.41 | 498 / 502 |
| uterus | 95% | 108531.38 | 162 / 170 | 92% | 455.67 | 424 / 459 |
| bladder | 81% | 126844.90 | 17 / 21 | 86% | 195.73 | 432 / 504 |
| intestine | 71% | 148085.35 | 682 / 966 | 90% | 141.73 | 473 / 527 |
| esophagus | 69% | 209341.56 | 990 / 1445 | 84% | 105.82 | 153 / 183 |
| stomach | 44% | 77870.32 | 157 / 359 | 88% | 213.64 | 251 / 286 |
| ovary | 37% | 18414.24 | 66 / 180 | 91% | 116.46 | 392 / 430 |
| breast | 19% | 8023.26 | 88 / 459 | 88% | 130.43 | 982 / 1118 |
| lung | 15% | 6714.34 | 89 / 578 | 88% | 141.25 | 1020 / 1155 |
| ureter | 0% | 0 | 0 / 0 | 100% | 208.72 | 1 / 1 |
| muscle | 100% | 477688.48 | 802 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 277036.60 | 1325 / 1335 | 0% | 0 | 0 / 0 |
| pancreas | 0% | 0 | 0 / 328 | 97% | 335.09 | 173 / 178 |
| skin | 22% | 10181.16 | 390 / 1809 | 65% | 68.57 | 305 / 472 |
| adrenal gland | 12% | 4798.94 | 32 / 258 | 67% | 108.05 | 154 / 230 |
| lymph node | 0% | 0 | 0 / 0 | 79% | 117.04 | 23 / 29 |
| kidney | 2% | 845.93 | 2 / 89 | 68% | 93.61 | 612 / 901 |
| heart | 69% | 33356.64 | 591 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 64% | 89.14 | 29 / 45 |
| thymus | 4% | 2204.38 | 29 / 653 | 59% | 45.42 | 359 / 605 |
| brain | 0% | 91.20 | 5 / 2642 | 55% | 47.46 | 390 / 705 |
| liver | 0% | 0 | 0 / 226 | 39% | 40.24 | 159 / 406 |
| eye | 0% | 0 | 0 / 0 | 24% | 13.74 | 19 / 80 |
| adipose | 21% | 11427.66 | 258 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 4% | 1418.68 | 9 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 265.20 | 4 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007015 | Biological process | actin filament organization |
| GO_0043462 | Biological process | regulation of ATP-dependent activity |
| GO_0006936 | Biological process | muscle contraction |
| GO_0005862 | Cellular component | muscle thin filament tropomyosin |
| GO_0015629 | Cellular component | actin cytoskeleton |
| GO_0005829 | Cellular component | cytosol |
| GO_0005884 | Cellular component | actin filament |
| GO_0046982 | Molecular function | protein heterodimerization activity |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0051015 | Molecular function | actin filament binding |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0003779 | Molecular function | actin binding |
| GO_0008307 | Molecular function | structural constituent of muscle |
| Gene name | TPM2 |
| Protein name | Tropomyosin beta chain (Beta-tropomyosin) (Tropomyosin-2) |
| Synonyms | TPM2b TMSB |
| Description | FUNCTION: Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization. . |
| Accessions | A0A2R8Y6A3 ENST00000378292.9 [P07951-2] ENST00000644325.1 ENST00000645482.3 [P07951-1] U3KQK2 A7XZE4 Q5TCU3 P07951 ENST00000329305.6 ENST00000607559.1 ENST00000647435.1 |