Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 9 studies | 31% ± 16% | |
type I pneumocyte | 8 studies | 22% ± 7% | |
basal cell | 6 studies | 28% ± 12% | |
fibroblast | 4 studies | 28% ± 6% | |
kidney loop of Henle epithelial cell | 4 studies | 18% ± 4% | |
connective tissue cell | 4 studies | 26% ± 8% | |
enterocyte | 4 studies | 26% ± 3% | |
respiratory goblet cell | 3 studies | 22% ± 3% | |
secretory cell | 3 studies | 30% ± 3% | |
ciliated cell | 3 studies | 29% ± 8% | |
brush cell | 3 studies | 26% ± 7% | |
goblet cell | 3 studies | 21% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 2294.16 | 89 / 89 | 99% | 33.73 | 890 / 901 |
intestine | 99% | 2723.17 | 961 / 966 | 99% | 33.31 | 521 / 527 |
lung | 100% | 1964.57 | 576 / 578 | 99% | 36.32 | 1138 / 1155 |
thymus | 100% | 1511.57 | 653 / 653 | 98% | 35.11 | 594 / 605 |
pancreas | 100% | 1151.89 | 327 / 328 | 98% | 54.74 | 175 / 178 |
uterus | 99% | 909.86 | 168 / 170 | 98% | 45.85 | 451 / 459 |
stomach | 99% | 963.86 | 356 / 359 | 96% | 25.48 | 275 / 286 |
bladder | 95% | 941.62 | 20 / 21 | 99% | 46.91 | 498 / 504 |
breast | 100% | 1065.55 | 457 / 459 | 90% | 16.92 | 1007 / 1118 |
esophagus | 97% | 2891.62 | 1399 / 1445 | 90% | 18.56 | 165 / 183 |
prostate | 98% | 976.29 | 240 / 245 | 88% | 18.90 | 444 / 502 |
ovary | 81% | 452.28 | 145 / 180 | 98% | 31.93 | 423 / 430 |
adrenal gland | 100% | 1322.83 | 258 / 258 | 69% | 13.87 | 159 / 230 |
skin | 83% | 931.65 | 1500 / 1809 | 82% | 17.35 | 386 / 472 |
liver | 71% | 463.99 | 161 / 226 | 91% | 33.13 | 371 / 406 |
brain | 15% | 59.40 | 402 / 2642 | 87% | 19.77 | 610 / 705 |
ureter | 0% | 0 | 0 / 0 | 100% | 23.14 | 1 / 1 |
adipose | 99% | 1120.71 | 1194 / 1204 | 0% | 0 | 0 / 0 |
spleen | 99% | 736.51 | 238 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 23.80 | 44 / 45 |
blood vessel | 94% | 624.56 | 1256 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 93% | 18.59 | 27 / 29 |
eye | 0% | 0 | 0 / 0 | 85% | 11.63 | 68 / 80 |
heart | 82% | 470.05 | 710 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 79% | 757.53 | 734 / 929 | 0% | 0 | 0 / 0 |
muscle | 19% | 123.98 | 150 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006739 | Biological process | NADP metabolic process |
GO_0005829 | Cellular component | cytosol |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0003960 | Molecular function | NADPH:quinone reductase activity |
GO_0070402 | Molecular function | NADPH binding |
GO_0048038 | Molecular function | quinone binding |
Gene name | TP53I3 |
Protein name | Quinone oxidoreductase PIG3 (EC 1.6.5.5) (NADPH:quinone reductase PIG3) (Tumor protein p53-inducible protein 3) (Protein PIG3) (p53-induced gene 3 protein) Tumor protein p53 inducible protein 3 Tumor protein p53 inducible protein 3, isoform CRA_c (cDNA FLJ61719, highly similar to quinone oxidoreductase) |
Synonyms | hCG_22385 PIG3 |
Description | FUNCTION: Catalyzes the NADPH-dependent reduction of quinones . Exhibits a low enzymatic activity with beta-naphthoquinones, with a strong preference for the ortho-quinone isomer (1,2-beta-naphthoquinone) over the para isomer (1,4-beta-naphthoquinone). Also displays a low reductase activity for non-quinone compounds such as diamine and 2,6-dichloroindophenol (in vitro) . Involved in the generation of reactive oxygen species (ROS) . . |
Accessions | Q53FA7 ENST00000335934.8 [Q53FA7-1] ENST00000407482.5 [Q53FA7-2] ENST00000413037.1 B4DMQ7 ENST00000238721.9 [Q53FA7-1] H7BZH6 |