TMT1B | OmnibusX

Name	Number of supported studies	Average coverage
enterocyte	5 studies	19% ± 4%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of TMT1B at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	5341.24	226 / 226	99%	286.74	402 / 406
kidney	92%	670.57	82 / 89	88%	105.18	789 / 901
intestine	48%	707.63	462 / 966	94%	68.36	496 / 527
thymus	62%	141.99	403 / 653	79%	141.41	479 / 605
pancreas	62%	90.23	204 / 328	77%	40.22	137 / 178
stomach	23%	27.95	81 / 359	91%	68.14	261 / 286
brain	50%	136.14	1329 / 2642	56%	134.30	392 / 705
spleen	95%	281.34	230 / 241	0%	0	0 / 0
heart	93%	3509.05	797 / 861	0%	0	0 / 0
lung	40%	100.30	234 / 578	47%	27.10	546 / 1155
ovary	1%	1.13	2 / 180	80%	48.70	346 / 430
muscle	78%	287.54	626 / 803	0%	0	0 / 0
adrenal gland	56%	95.30	145 / 258	10%	4.51	22 / 230
skin	30%	86.07	544 / 1809	31%	13.56	144 / 472
peripheral blood	58%	391.86	537 / 929	0%	0	0 / 0
esophagus	2%	2.37	22 / 1445	47%	29.32	86 / 183
bladder	0%	0	0 / 21	41%	23.69	208 / 504
lymph node	0%	0	0 / 0	31%	7.83	9 / 29
uterus	4%	2.95	6 / 170	23%	10.81	105 / 459
adipose	21%	47.78	253 / 1204	0%	0	0 / 0
breast	14%	42.01	62 / 459	5%	1.80	59 / 1118
blood vessel	11%	22.07	147 / 1335	0%	0	0 / 0
prostate	8%	9.06	19 / 245	0%	0.10	2 / 502
tonsil	0%	0	0 / 0	2%	4.07	1 / 45
eye	0%	0	0 / 0	1%	0.62	1 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0032259	Biological process	methylation
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0005829	Cellular component	cytosol
GO_0005811	Cellular component	lipid droplet
GO_0018708	Molecular function	thiol S-methyltransferase activity
GO_0008757	Molecular function	S-adenosylmethionine-dependent methyltransferase activity
GO_0008168	Molecular function	methyltransferase activity

Gene name	TMT1B
Protein name	Thiol S-methyltransferase TMT1B (EC 2.1.1.9) (Methyltransferase-like protein 7B) (Thiol S-methyltransferase METTL7B)
Synonyms	UNQ594/PRO1180 METTL7B
Description	FUNCTION: Thiol S-methyltransferase that catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to alkyl and phenolic thiol-containing acceptor substrates. Together with TMT1B accounts for most of S-thiol methylation activity in the endoplasmic reticulum of hepatocytes. Selectively methylates S-centered nucleophiles from metabolites such as hydrogen sulfide and dithiothreitol. .
Accessions	Q6UX53 ENST00000394252.4

TMT1B report